[Fundamental aspects of oncogenesis].

[Fundamental aspects of oncogenesis].
Bull Cancer. 2020 Oct 07;:
Authors: Lemaire J, Larrue R, Perrais M, Cauffiez C, Pottier N
Abstract
Tumorigenesis has traditionally been considered as a multi-step process involving the activation of oncogenes as well as the inactivation of tumor suppressor genes. However, the mechanisms driving cancer initiation and progression are not restricted to molecular alterations and instead should be viewed as a complex process that interfaces with the entire organism. This didactic review provides an integrated and global view of the key fundamental principles of cancer development.
PMID: 33039132 [PubMed - as supplied by publisher]

Source: Bulletin du Cancer - October 7, 2020 Category: Cancer & Oncology Authors: Lemaire J, Larrue R, Perrais M, Cauffiez C, Pottier N Tags: Bull Cancer Source Type: research