What are Potential Complications of Ichthyosis?
Discussion
Ichthyosis is a large group of dermatological disorders which are caused by abnormal epidermal differentiation. The term ichthys means fish and refers to the scale-like dermatological pattern seen in these disorders.
Acquired ichthyosis is rare but more common in adults than children and has a rough, dry skin with prominent scaling, distributed symmetrically on the trunk and limbs (especially extensor surfaces), and is associated with autoimmune, infectious diseases, metabolic and malignant causes. Congenital or inherited ichthyosis is divided into non-syndromic (more common) and syndromic forms (generally very rare, e.g. Netherton syndrome or Sjogren-Larsson syndrome, Refsum syndrome, etc.). Specific diagnosis in the newborn period is not necessarily helpful, but with aggressive support, over time the specific clinical entity often becomes apparent. Treatment is also similar.
Some examples include:
Ichthyosis vulgaris
Most common and mildest form
“…xerosis, scaling, pruritis and eczema, and it is strongly associated with atopic manifestations.” Back and lower legs are more affected.
Starts after 2 months of age, better in the summer
Recessive X-linked ichthyosis
Second most common
Dark brown scale on entire body
Starts around birth and does not improve with age
Harlequin ichthyosis
Autosomal recessive due to ABCA12 gene, very rare
Has thick, armor or plate-like scales which can cause contractures
Babies are often born premature
Collodion ba...
Source: PediatricEducation.org - Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
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