Patent ductus arteriosus

Patent ductus arteriosus Ductus arteriosus normally closes by 72 hours after birth. The structure becomes fibrotic later and remains as the ligamentum arteriosus. Endothelium of mature ductus responds to oxygen which acts as the stimulus of constriction as it receives oxygenated blood from the lungs. Premature ductus does not respond to oxygen that well. Patent ductus arteriosus is much more common in the premature infant than the mature infant. The higher the prematurity, the higher the chance of having a patent ductus arteriosus (PDA). PDA can occur as part of the congenital rubella syndrome. Patent ductus arteriosus – angio Patent ductus arteriosus demonstrated by an aortogram. Patent ductus arteriosus with left to right shunt increases pulmonary blood flow, pulmonary venous return and dilatation of left atrium, left ventricle and aorta. When there is a large flow, pulmonary arteries are dilated and long standing cases develop severe pulmonary hypertension with flow reversal (Eisenmenger reaction). The patent ductus arteriosus connects to the aorta distal to the origin of left subclavian. Hence reversal of shunt produces desaturation mostly in the lower part of the body, leading to differential cyanosis and clubbing. Upper body receives saturated blood from the aorta prior to the right to left shunt and has no cyanosis. Clinical findings in PDA Pulse is high volume in PDA because the flow from aorta into the low resistance pulmonary circuit acts as an aortic runoff. ...
Source: Cardiophile MD - Category: Cardiology Authors: Tags: HBC Atypical PDA eddy sounds Gibson’s area Gibson’s murmur inverted Y shaped pattern of calcification train in tunnel murmur Source Type: blogs