High density of stroma-localized CD11c-positive macrophages is associated with longer overall survival in high-grade serous ovarian cancer.

CONCLUSIONS: Our study supports the existence of clinically relevant marker- and localization defined macrophage subsets in HGSC, which are independently regulated. Moreover, it suggests stromal CD11c as a novel prognostic marker in HGSC. PMID: 33032823 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/33032823?dopt=Abstract

Source: Gynecologic Oncology - October 5, 2020 Category: Cancer & Oncology Authors: Corvigno S, Mezheyeuski A, De La Fuente LM, Westbom-Fremer S, Carlson JW, Fernebro J, Åvall-Lundqvist E, Kannisto P, Hedenfalk I, Malander S, Rolny C, Dahlstrand H, Östman A Tags: Gynecol Oncol Source Type: research