Homotherapy for heteropathy active components and mechanisms of Qiang-Huo-Sheng-Shi decoction for treatment of rheumatoid arthritis and osteoarthritis.

This study provides new insight into the molecular mechanisms behind how QHSSD presents homotherapy-for-heteropathy therapeutic efficacy in both OA and RA. For the first time, a two-disease model was linked with a TCM formula using network pharmacology to identify the key active components and understand the common mechanisms of its multi-pathway regulation. This study will inspire more innovative and important studies on the modern research of TCM formulas.
PMID: 33035753 [PubMed - as supplied by publisher]

Source: Computational Biology and Chemistry - October 1, 2020 Category: Bioinformatics Authors: Shi YY, Li YQ, Xie X, Zhou YT, Zhang Q, Yu JL, Li P, Mi N, Li F Tags: Comput Biol Chem Source Type: research