The primary treatment of prostate cancer with high-intensity focused ultrasound: A systematic review and meta-analysis

Conclusions: Early evidence suggested the partial-gland HIFU was safer than whole-gland HIFU, and they had similar oncological outcomes. More prospective randomized controlled trials of whole-gland and partial-gland HIFU for PCa was needed.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research

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Reggie Dye went 15 years without seeing a physician, in part because he had always been incredibly healthy. He regularly does high-intensity worksouts, enjoys hiking, golf, and can't remember the last time he even had a cold. But a preventative health evaluation incentive program his company offered in 2016 taught him that even the healthiest individuals are not immune to prostate cancer. After two prostate-specific antigen (PSA) screening tests, followed by additional testing, Dye was diagnosed with localized prostate cancer. At first, he was given the choice of active surveillance, als...
Source: MDDI - Category: Medical Devices Authors: Tags: Regulatory and Compliance Source Type: news
Patches made from human placenta could prevent men becoming impotent following prostate cancer surgery. Incontinence and erectile dysfunction can occur in up to seven in ten men.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
CONCLUSIONS: There was no impact of timing between RP and RT on urinary, bowel, and erectile adverse events related to RT. Thus, our RTOG 9601 post hoc analysis challenges the current belief that early postsurgical RT compromises functional outcomes more than late RT and support additional research to evaluate the perceived benefit in terms of adverse effects by prolonging the time between RP and RT. PMID: 31653564 [PubMed - as supplied by publisher]
Source: Urologic Oncology - Category: Urology & Nephrology Authors: Tags: Urol Oncol Source Type: research
Medical device companies attempting to market a new treatment in the U.S. often make the erroneous assumption that winning FDA approval is the final destination, and success is theirs. In fact, going through the regulatory process is only the halfway point. The grueling path from FDA approval to reimbursement is like a treacherous walk through Death Valley and many companies don’t make it through. In this case study, I discuss the trials and triumphs of bringing robotic high intensity focused ultrasound (HIFU), a non-invasive procedure for localized prostate cancer, to the U.S.&Aci...
Source: MDDI - Category: Medical Devices Authors: Tags: Regulatory and Compliance Business Source Type: news
Abstract While radiotherapy is widely used in cancer treatment, the benefits can be limited by radiation-induced damage to neighboring healthy tissues. We previously demonstrated that the anti-inflammatory compound dimethylaminoparthenolide (DMAPT) selectively induces radiosensitivity in prostate tumor tissue from transgenic adenocarcinoma of mouse prostate (TRAMP), while simultaneously protecting healthy tissues from 6 Gy whole-body radiation-induced apoptosis. Here, we examined the radioprotective effect of DMAPT on fibrosis in normal tissues after a partial-body fractionated radiation protocol that more closely...
Source: Radiation Research - Category: Physics Authors: Tags: Radiat Res Source Type: research
Surgery for prostate cancer may cause incontinence and impotence. Michael Wellin, 71, from London, underwent a new procedure that reduces those risks.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Conclusions: Men had entrenched ideas about what manhood entailed. The review found that men’s sense of masculinity was diminished posttreatment of prostate cancer. They felt that they could not exercise their manliness because of the adverse effects associated with prostate cancer treatment. Implications for Practice: More support and communication throughout the process are required to better inform patients of the outcomes of treatment. In addition, it would be beneficial to have open forums through which to encourage men to talk frankly about their masculine identities.
Source: Cancer Nursing - Category: Nursing Tags: Articles Source Type: research
AbstractPurpose of ReviewDue to the proximity of the rhabdosphincter and cavernous nerves to the membranous urethra, reconstruction of membranous urethral stricture implies a risk of urinary incontinence and erectile dysfunction. To avoid these complications, endoscopic management of membranous urethral strictures is traditionally favored, and bulboprostatic anastomosis is reserved as the main classical approach for open reconstruction of recalcitrant membranous urethral stricture. The preference for the anastomotic urethroplasty among reconstructive urologists is likely influenced by the familiarity and experience with tr...
Source: Current Urology Reports - Category: Urology & Nephrology Source Type: research
This study adds to the discouraging screening literature, and again, simply does not support screening of asymptomatic individuals,” he said. Fortunately, Garnick added, men diagnosed with prostate cancer following a PSA test may not have to be treated either in the short or long term. Depending on tumor characteristics, some can opt to have their cancer monitored with active surveillance, which relies on periodic prostate biopsies or MRI to look for new signs that treatment may be necessary. “Hopefully, current research that uses sophisticated genetic testing or biomarkers of prostate cancer may help provide m...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Cancer Health Men's Health Prostate Health Screening Source Type: blogs
Purpose of review Options for prostate cancer management are rapidly expanding. The recent advent of MRI technology has led to guided prostate biopsies by radiologists working in-bore or by urologists using MR/US fusion technology. The resulting tumor visualization now provides the option of focal therapy. Currently available are highly directed energies – focused ultrasound (HIFU), cryotherapy, and laser – all offering the hope of curing prostate cancer with few side effects. Recent findings MRI now enables visualization of many prostate cancers. MR/US fusion biopsy makes possible the targeted biopsy of s...
Source: Current Opinion in Urology - Category: Urology & Nephrology Tags: ROBOTIC SURGERY IN UROLOGY: FACTS AND REALITY: Edited by Alexandre de la Taille and Jim C. Hu Source Type: research
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