The role of CD8  + T lymphocytes in chronic obstructive pulmonary disease: a systematic review

ConclusionsNot only is the number of CD8  + T-cells increased in COPD, these cells have increased capacity to exert effector functions and are likely to contribute to disease pathogenesis. Several mechanisms highlighted show promise for future investigation to consolidate current knowledge.
Source: Inflammation Research - Category: Research Source Type: research

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This study was conducted on a sample of 42 COPD subjects with patient history, COPD assessment test (CAT) and spirometry. 5STST performance time and the number 30s-STST repetitions showed differences of statistical significance in COPD subjects considered to be more symptomatic and in subjects with high risk of future exacerbations. Both STSTs correlated significantly with forced expiratory volume in one second % predicted (FEV1%), CAT, number of acute exacerbations in the past year and number of hospitalized exacerbations in the past year. STST performance correlates significantly with items of the CAT questionnaire that ...
Source: COPD: Journal of Chronic Obstructive Pulmonary Disease - Category: Respiratory Medicine Tags: COPD Source Type: research
Publication date: Available online 8 October 2020Source: Respiratory Physiology &NeurobiologyAuthor(s): Vlasios Skopas, Dimitrios Papadopoulos, Nikolaos Trakas, Eleni Papaefstathiou, Charalampos Koufopoulos, Demosthenes Makris, Zoe Daniil, Konstantinos Gourgoulianis
Source: Respiratory Physiology and Neurobiology - Category: Respiratory Medicine Source Type: research
Conclusion: The current study provides the first evidence regarding the status of frailty in older Chinese adults with hypertension.
Source: Journal of Hypertension - Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology and risk factors Source Type: research
Authors: Utley C, Gold MH, Hall M Abstract Background/Significance of problem: Atopic Dermatitis (AD) is a common, chronic, inflammatory dermatosis and skin disease that follows a relapsing pattern and requires a dynamic stepwise approach to management.Providers feel comfortable treating chronic disease states with a guided tool or care plan in many chronic diseases.Care plans used in many chronic diseases such as asthma, diabetes, and COPD have demonstrated effectiveness in disease and healthcare provider management.There is an unmet need for a universal AD care plan for providers. Clinical question/project purpos...
Source: Journal of Drugs in Dermatology - Category: Dermatology Tags: J Drugs Dermatol Source Type: research
Elderly patients with impaired vision, cognitive decline or motor/sensory disturbances of their fingers suffering from chronic-obstructive pulmonary disease (COPD) encounter difficulties in handling inhaler de...
Source: BMC Geriatrics - Category: Geriatrics Authors: Tags: Research article Source Type: research
Gastrointestinal symptoms are prevalent extrapulmonary systemic manifestations of Chronic Obstructive Pulmonary Disease (COPD), but have been rarely studied. We dissected the perturbations in intestinal function in human patients with COPD using comprehensive metabolic and physiological approaches.
Source: Clinical Nutrition - Category: Nutrition Authors: Tags: Original article Source Type: research
ConclusionPressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat.
Source: Intensive Care Medicine - Category: Intensive Care Source Type: research
npj Primary Care Respiratory Medicine, Published online: 09 October 2020; doi:10.1038/s41533-020-00198-5Pragmatic trial on inhaled corticosteroid withdrawal in patients with COPD in general practice
Source: npj Primary Care Respiratory Medicine - Category: Primary Care Authors: Source Type: research
Conditions:   COPD;   Chronic Obstructive Pulmonary Disease Interventions:   Other: 1-min STS test: adjusted;   Other: 1-min STS test: standardized Sponsors:   Thomas Riegler;   University of Zurich Recruiting
Source: - Category: Research Source Type: clinical trials
Dr Aaron Holley explains the evidence that backs up the new ATS guideline for COPD management and how it contradicts the GOLD recommendations.Medscape Critical Care
Source: Medscape Critical Care Headlines - Category: Intensive Care Tags: Pulmonary Medicine Viewpoint Source Type: news
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