Inhibiting HMGB1-RAGE axis prevents pro-inflammatory macrophages/microglia polarization and affords neuroprotection after spinal cord injury

Spinal cord injury (SCI) favors a persistent pro-inflammatory macrophages/microglia-mediated response with only a transient appearance of anti-inflammatory phenotype of immune cells. However, the mechanisms co...

Source: Journal of Neuroinflammation - October 9, 2020 Category: Neurology Authors: Hong Fan, Hai-Bin Tang, Zhe Chen, Hu-Qing Wang, Lei Zhang, Yu Jiang, Tao Li, Cai-Feng Yang, Xiao-Ya Wang, Xia Li, Sheng-Xi Wu and Gui-Lian Zhang Tags: Research Source Type: research