Associations of Depressive Symptoms with All-Cause and Cause-Specific Mortality by Race in A Low-Socioeconomic Population: A Report from the Southern Community Cohort Study.

Associations of Depressive Symptoms with All-Cause and Cause-Specific Mortality by Race in A Low-Socioeconomic Population: A Report from the Southern Community Cohort Study. Am J Epidemiol. 2020 Oct 09;: Authors: Cui Y, Zheng W, Steinwandel M, Cai H, Sanderson M, Blot W, Shu XO Abstract Depression is a leading cause of disability in the United States, but its impact on mortality among racially diverse, low-socioeconomic populations is largely unknown. Using data from the Southern Community Cohort Study, 2002-2015, we prospectively evaluated the associations of depressive symptoms with all-cause and cause-specific mortality in 67,781 black (72.3%) and white (27.7%) adults, predominantly with a low-socioeconomic status. Baseline depressive symptoms were assessed using the ten-item Center for Epidemiological Studies Depression Scale. The median follow-up time was 10.0 years. Multivariate Cox regression was used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for mortality in association with depressive symptoms. Mild/moderate/severe depressive symptoms were associated with increased all-cause (HR=1.12, 95%CI: 1.03-1.22; HR=1.17, 95%CI: 1.06-1.29; HR=1.15, 95%CI: 1.03-1.28, respectively) and cardiovascular disease mortality (HR=1.23, 95%CI: 1.05-1.44; HR=1.18, 95%CI: 0.98-1.42; HR=1.43, 95%CI: 1.17-1.75, respectively) in whites but not in blacks (Pinteraction< 0.001, for both). Mild/moderate/severe depressive sympto...
Source: Am J Epidemiol - Category: Epidemiology Authors: Tags: Am J Epidemiol Source Type: research