Trends in Acute Lymphoblastic Leukemia Incidence in the US from 2000-2016: an Increased Risk in Latinos Across All Age Groups.

Trends in Acute Lymphoblastic Leukemia Incidence in the US from 2000-2016: an Increased Risk in Latinos Across All Age Groups. Am J Epidemiol. 2020 Oct 09;: Authors: Feng Q, de Smith AJ, Vergara-Lluri M, Muskens IS, McKean-Cowdin R, Kogan S, Brynes R, Wiemels JL Abstract Incidence trends in acute lymphoblastic leukemia (ALL) demonstrate disparities by race and ethnicity. We used data from the Surveillance, Epidemiology and End Results Registry to evaluate patterns in ALL incidence from 2000-2016, including the association between the percent of people born in a foreign country at the county level and ALL incidence. Among 23,829 individuals of all ages diagnosed with ALL, 8,297 (34.8%) were Latinos, 11,714 (49.2%) were non-Latino (NL) Whites, and 1,639 (6.9%) were NL Blacks. Latinos had the largest increase in the age-adjusted incidence rate (AAIR) in this period compared to other race/ethnicities for both children and adults: AAIR was 1.6 times higher for Latinos (AAIR=2.43;95%CI: 2.37,2.49) compared to NL Whites (AAIR=1.56;95%CI:1.53,1.59; P<0.01). The AAIR for all children increased approximately 1% per year from 2000-2016 (annual percent change=0.97;95%CI:0.67,1.27), with the highest increase in Latinos (annual percent change=1.18;95%CI:0.76,1.60). In multivariable models evaluating the contribution of % of the county residents that were foreign born to ALL risk, a positive association was found for percentage of foreign born f...
Source: Am J Epidemiol - Category: Epidemiology Authors: Tags: Am J Epidemiol Source Type: research