Catastrophic APS in the Context of Other Thrombotic Microangiopathies

This article aims to review the main diseases included in the differential diagnosis of CAPS in the context of other thrombotic microangiopathies.
Source: Current Rheumatology Reports - Category: Rheumatology Source Type: research

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Publication date: Available online 14 December 2019Source: Respiratory Medicine Case ReportsAuthor(s): Franklin Argueta, David Villafuerte, Jose Castaneda-Nerio, Jay Peters, Carlos RestrepoAbstractFibrosing mediastinitis is a rare disorder characterized by the invasive proliferation of fibrous tissue within the mediastinum. This fibrosis can result in compression of intrathoracic structures including the pulmonary vasculature leading to clinical symptoms and complications like pulmonary hypertension. Here, we present two cases of young patients with fibrosing mediastinitis complicated by pulmonary artery stenosis requiring...
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
Source: BMJ Comments - Category: General Medicine Source Type: forums
This study aimed to explore the association between serum syndecan-1 and glypican-3 levels and the adverse perinatal outcome as well as the responses to the treatment of ursodeoxycholic acid (UDCA).MethodsThis prospective, case control study included 88 pregnant women (44 women with ICP and 44 healthy controls). The primary end points were the perinatal outcome and the response to UDCA therapy. A logistic regression model was used to identify the independent risk factors of adverse pregnancy outcomes and reduced response to UDCA therapy.ResultsWomen with ICP had significantly higher serum syndecan-1 (1.27 ± 0.36 ng/...
Source: Hepatobiliary and Pancreatic Diseases International - Category: Gastroenterology Source Type: research
A drink that is linked to high blood pressure and increased risk of heart problems. → Support PsyBlog for just $4 per month. Enables access to articles marked (M) and removes ads. → Explore PsyBlog's ebooks, all written by Dr Jeremy Dean: Accept Yourself: How to feel a profound sense of warmth and self-compassion The Anxiety Plan: 42 Strategies For Worry, Phobias, OCD and Panic Spark: 17 Steps That Will Boost Your Motivation For Anything Activate: How To Find Joy Again By Changing What You Do
Source: PsyBlog | Psychology Blog - Category: Psychiatry & Psychology Authors: Tags: Blood Pressure Source Type: blogs
Publication date: January 2020Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 129, Issue 1Author(s): Dalal Alhajji, Yoon Ah Danskin, Bridget O'hara, Karl Armand Solano, Jessica Flynn, Elyn Riedel, Sae Hee Kim Yom, Cherry EstiloObjectivesOsteoradionecrosis (ORN) is a complication of head and neck radiation therapy (RT) and is associated with significant morbidity. The incidence of ORN is variable, and it has been speculated to be lower with advanced RT techniques. Risk factors that have been associated with the development of ORN mainly include trauma and a radiation dose to the head and neck ...
Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - Category: ENT & OMF Source Type: research
Publication date: January 2020Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 129, Issue 1Author(s): RAYZA RECHETNICOU, MARIA FERNANDA BARTHOLO SILVA, NATÁLIA SILVA ANDRADE, KAREM LOPEZ ORTEGA, MARINA HELENA CURY GALLOTTINIObjectiveThe life expectancy of people positive for human immunodeficiency virus (HIV) has increased since the advent of combined antiretroviral therapy (CART). There was a decrease in opportunistic infections in this population, but on the other hand, there were side effects to medications and medical conditions related to longevity. The main of this prospective stu...
Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - Category: ENT & OMF Source Type: research
We report 2 cases of oral squamous cell carcinoma in male patients with FA who underwent hematopoietic stem cell transplantation. Both patients presented with oral lichenoid lesions, compatible with chronic graft vs host disease. In the first case, a 16-year-old patient presented with an extensive infiltrative and necrotic lesion on the border of the tongue.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - Category: ENT & OMF Authors: Source Type: research
A 63-year-old white male presented with maxillary gingival swelling for a 6-month duration. Medical history revealed diabetes and hypertension. Extraoral examination was noncontributory. Intraoral exam showed a red bleeding lobulated nodule measuring 5.0  × 3.0 cm in the left maxillary gingiva. The presumptive diagnosis was nonneoplastic reactive lesion. An incisional biopsy was performed and histopathologic diagnosis was unspecific malignant neoplasm. The initial immunohistochemical panel was inconclusive.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - Category: ENT & OMF Authors: Source Type: research
Fanconi anemia (FA) is a rare autosomal recessive genetic disorder, characterized by congenital malformations of certain organs, thrombocytopenia, and chronic anemia due to the progressive failure of bone marrow, with an elevated risk of infections and bleeding. A 24-year-old male patient with FA was referred to our clinic with a chief complaint of cheek biting and resultant significant bleeding. During clinical evaluation, a traumatic ulcer in the left buccal mucosa was observed with a massive blood clot formed inappropriately along with continuous bleeding.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - Category: ENT & OMF Authors: Source Type: research
Fanconi Anemia (FA) is a rare autosomal recessive genetic disorder that can cause bone marrow failure and increased risk for malignancies. Hematopoietic stem cell transplantation (HSCT) in patients with FA also increases the risk of tumors. The following reported case is of a male patient, diagnosed with AF, with a history of HSCT at 4 years of age. At 14 years old, he presented with a painless ulcerated lesion, irregular borders, 3 cm in size, on the right lateral border of the tongue with a 20-day course, associated with a submandibular lymphadenopathy.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - Category: ENT & OMF Authors: Source Type: research
More News: Anemia | Antiphospholipid Syndrome | Cancer & Oncology | Hemolytic Uremic Syndrome (HUS) | Hughes Syndrome | Hypertension | Microangiopathic Hemolytic Anemia | Pregnancy | Rare Diseases | Rheumatology | Thrombocytopenia