Opioid-free general anesthesia and induced recovery from anesthesia in a patient with myotonic dystrophy type-1: a case report

Publication date: Available online 9 October 2020Source: Brazilian Journal of Anesthesiology (English Edition)Author(s): Hande Gurbuz Aytuluk, Kemal Tolga Saracoglu
Source: Brazilian Journal of Anesthesiology - Category: Anesthesiology Source Type: research

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CONCLUSION: The data support the hypothesis that an enlarged prostate in MOR may contribute to voiding dysfunction involving activation of P2X2/3R, which enhances a prostate-bladder reflex. This reflex may increase bladder afferent transmission and activation of increased prostate innervation, leading to voiding dysfunction. PMID: 33017896 [PubMed]
Source: International Neurourology Journal - Category: Urology & Nephrology Tags: Int Neurourol J Source Type: research
Trigeminocardiac reflex (TCR) is the paroxysmal dysautonomia that results from manipulation of the sensory branches of the fifth cranial nerve, resulting in gastric hypermotility, cardiac dysrhythmias, asystole, and bradycardia. It is considered to be a maxillary and mandibular manifestation of the oculocardiac reflex (OCR). Authors have attempted to stratify the surgical risk for TCR based on published cases. However, the role of specific anesthetic agents in modulating TCR remains incompletely understood.
Source: Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Authors: Source Type: research
Conclusion: Nebulised dexmedetomidine effectively blunts the stress response to laryngoscopy and intubation with no adverse effects.
Source: Indian Journal of Anaesthesia - Category: Anesthesiology Authors: Source Type: research
During emergence from anesthesia after partial and total laryngectomy, excessive airway reflex and systemic hypertension may lead to subcutaneous emphysema, hemorrhage or pneumothorax.
Source: BMC Anesthesiology - Category: Anesthesiology Authors: Tags: Research article Source Type: research
We described six case series of successfully performed ESP block for postoperative analgesia in various abdominal surgeries such as unilateral open inguinal hernia repair with a supraumbilical hernia, ileostomy reversal surgery, open diaphragmatic hernia repair, laparoscopic cholecystectomy, and abdominal abscess evacuation.
Source: Saudi Journal of Anaesthesia - Category: Anesthesiology Authors: Source Type: research
This study aimed to elucidate the role of PVN‒RVLM neurons in the maintenance of resting renal sympathetic nerve activity (RSNA) after myocardial infarction (MI). In male rats, the left coronary artery was chronically ligated to induce MI. The rats received PVN microinjections of an adeno‒associated viral (AAV) vector encoding an archaerhodopsin T (ArchT) with the reporter eYFP. The ArchT rats had abundant distributions of eYFP‒labelled, PVN‒derived axons in the RVLM. In anesthetized ArchT rats with MI (n = 12), optogenetic inhibition of the PVN‒RVLM pathway achieved by 532‒nm‒wavelength laser illumination to...
Source: American Journal of Physiology. Heart and Circulatory Physiology - Category: Physiology Authors: Tags: Am J Physiol Heart Circ Physiol Source Type: research
We present a case of a sizeable vagal schwannoma that was resected through a lateral suboccipital approach in semisitting position. An extra-axial lesion, occupying the left cerebellomedullary cistern and extending from the pontomedullary junction to the jugular foramen was incidentally discovered in a 40-year-old woman afflicted with secondary progressive multiple sclerosis during repeated magnetic resonance imaging (Fig. 1). On physical examination, a mild deviation of the uvula to the right and a diminished gag reflex were observed. The patient was referred to our department after considerable growth of the lesion was n...
Source: Journal of Neurological Surgery Part B: Skull Base - Category: Neurosurgery Authors: Tags: Skull Base: Operative Videos Source Type: research
Authors: Palladino A, De Bernardo M, Scutifero M, Lanza M, De Querquis S, Rosa N, Politano L Abstract Myotonic dystrophy (DM1) is the most common muscle disease in adults, affecting approximately 1:8000 individuals, characterized by myotonia and muscular wasting and a multisystemic involvement that includes heart, brain, respiratory and endocrine system, and eye. Conduction system is selectively involved, often causing cardiac sudden death. Early onset posterior subcapsular cataract is a characteristic feature of myotonic dystrophy, requiring surgical treatment. However, DM1 is associated with many anesthetic hazar...
Source: Acta Myologica - Category: Neurology Tags: Acta Myol Source Type: research
Interleukin-1β in hypothalamic paraventricular nucleus mediates excitatory renal reflex. Pflugers Arch. 2020 Sep 11;: Authors: Zheng F, Ye C, Wan GW, Zhou B, Tong Y, Lei JZ, Chen Q, Li YH, Kang YM, Zhu GQ Abstract Chemical stimulation of kidney causes sympathetic activation and pressor responses in rats. The excitatory renal reflex (ERR) is mediated by angiotensin type 1 receptor (AT1R) and superoxide anions in hypothalamic paraventricular nucleus (PVN). The aim of this study is to determine whether interleukin-1β (IL-1β) in the PVN mediates the ERR, and whether the IL-1β productio...
Source: Pflugers Archiv : European Journal of Physiology - Category: Physiology Authors: Tags: Pflugers Arch Source Type: research
Conclusions: Although there was a significant correlation between NL and NP values as well as with clinical examination of the PLR, the 2 devices were not always interchangeable, especially for the evaluation of pupillary latency.
Source: Journal of Neurosurgical Anesthesiology - Category: Anesthesiology Tags: Clinical Investigations Source Type: research
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