Iodine nutrition status of women after 10 years of Lipiodol supplementation: a cross-sectional study in Xinjiang, China.

This study examined the contribution of long-term use of Lipiodol capsules, as a supplement to iodized salt to the control of iodine deficiency disorders among women in Xinjiang of China. A total of 1220 women (women of childbearing age who were neither pregnant nor lactating, pregnant women, and lactating women) across Kashgar, Aksu, Turpan, and Yili Prefectures were surveyed in 2017. Lipiodol capsules were administered twice yearly in Kashgar and once yearly in Aksu and Turpan, but not in Yili. Urinary iodine concentration (UIC), FT3, FT4, TgAb, TPOAb, and thyroid volume values were assessed. All the women in the four areas were in a state of non-iodine deficiency by UIC. Also, the UICs were higher than adequate in Kashgar and Aksu (619.4 vs 278.6 μg/L). Thyroid hormone levels differed significantly in Turpan and Yili (FT3: 4.4 vs 4.6 pmol/L, FT4: 13.8 vs 14.2 pmol/L, TSH: 2.0 vs 2.7 mIU/L), but did not differ significantly in Kashgar, Aksu, and Yili. Comparatively, the four areas did not differ significantly with regards to thyroid nodules, autoimmune thyroiditis, or goiter. However, the detection rates of subclinical hypothyroidism (16.6%) and total thyroid dysfunction (25.4%) were higher among women in Yili. The findings suggested that supplementation with Lipiodol capsules had improved the iodine nutrition status of women in iodine-deficient areas of Xinjiang since 2006. To avoid negative effects of excess iodine, we suggest a gradual discontinuation of Lipiodol caps...
Source: The British Journal of Nutrition - Category: Nutrition Authors: Tags: Br J Nutr Source Type: research

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Publication date: 15 February 2021Source: Journal of Hazardous Materials, Volume 404, Part AAuthor(s): Zhongyi Zhang, Wen-Xiong Wang, Nengjian Zheng, Yansheng Cao, Hongwei Xiao, Renguo Zhu, Hui Guan, Huayun Xiao
Source: Journal of Hazardous Materials - Category: Environmental Health Source Type: research
Publication date: 15 February 2021Source: Journal of Hazardous Materials, Volume 404, Part BAuthor(s): Jinsoo Lee, Seong-Jin Choi, Ji-Seong Jeong, Sang Yun Kim, Sang-Hyub Lee, Mi Jin Yang, Seung-Jin Lee, Young-Jun Shin, Kyuhong Lee, Eun Ju Jeong, Sang-Yoon Nam, Wook-Joon Yu
Source: Journal of Hazardous Materials - Category: Environmental Health Source Type: research
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Source: Food and Nutrition Research - Category: Nutrition Authors: Tags: Food Nutr Res Source Type: research
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Source: Journal of Pregnancy - Category: OBGYN Tags: J Pregnancy Source Type: research
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Source: Journal of Pregnancy - Category: OBGYN Tags: J Pregnancy Source Type: research
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Source: Journal of Pregnancy - Category: OBGYN Tags: J Pregnancy Source Type: research
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Source: Ecology of Food and Nutrition - Category: Nutrition Tags: Ecol Food Nutr Source Type: research
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Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research
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Source: Chemosphere - Category: Chemistry Authors: Tags: Chemosphere Source Type: research
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Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
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