The complex genetics of epigenetics in urothelial carcinomas

Nature Reviews Urology, Published online: 09 October 2020; doi:10.1038/s41585-020-00386-5Cancer sequencing studies have revealed that urothelial carcinomas harbour recurrent mutations in multiple genes that control epigenetics. A major challenge for basic and clinical researchers is to convert this genetic information into biological and pathological insights, as well as to tailor novel therapeutic modalities for individual patients with bladder cancer.
Source: Nature Reviews Urology - Category: Urology & Nephrology Authors: Source Type: research