Investigation of low dose cabazitaxel potential as microtubule stabilizer in experimental model of Alzheimer's disease: Restoring neuronal cytoskeleton.

CONCLUSION: The above findings suggested that CBZ at low dose show neuroprotective effects against ICV-STZ induced microtubule-associated tau protein hyperphosphorylation in rats and may be an effective agent for the preventive treatment of AD.
PMID: 33030130 [PubMed - as supplied by publisher]

Source: Current Alzheimer Research - October 7, 2020 Category: Neurology Authors: Duggal P, Jadaun KS, Siqqiqui EM, Mehan S Tags: Curr Alzheimer Res Source Type: research