Is There a Correlation Between Sarcopenia and Aortic Aneurysm Morphometry?

Low muscle mass is common in patients with abdominal aortic aneurysm (AAA) and is associated with reduced post-operative survival,1 frailty, and acute and chronic disease. AAA is due to connective tissue abnormalities influenced by enzymatic activity. Matrix metalloproteinases, which are implicated in this process, have also been shown to affect muscle development.2 It is unclear, however, if low muscle mass is related to the anatomy and evolution of AAA. It was hypothesised that low muscle mass, measured by total psoas area (TPA), is associated with certain features of aneurysmal disease in the abdominal aorta, which may determine suitability for infrarenal endovascular aneurysm repair.
Source: European Journal of Vascular and Endovascular Surgery - Category: Surgery Authors: Tags: Research letter Source Type: research