T2DM Links to Risk for Dementia Differ by Type, Glycemic Control

FRIDAY, Oct. 9, 2020 -- Patients with type 2 diabetes (T2D) are more likely to develop vascular dementia and nonvascular dementia compared with controls without diabetes, according to a study presented at the annual meeting of the European...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news

Related Links:

Rates of dementia, cognitive decline in people with type 2 diabetes taking metformin were similar to those without diabetes.Medscape Medical News
Source: Medscape Psychiatry Headlines - Category: Psychiatry Tags: Neurology & Neurosurgery News Source Type: news
Type 2 diabetes doubles the risk of cognitive problems and dementia. → Support PsyBlog for just $5 per month. Enables access to articles marked (M) and removes ads. → Explore PsyBlog's ebooks, all written by Dr Jeremy Dean: Accept Yourself: How to feel a profound sense of warmth and self-compassion The Anxiety Plan: 42 Strategies For Worry, Phobias, OCD and Panic Spark: 17 Steps That Will Boost Your Motivation For Anything Activate: How To Find Joy Again By Changing What You Do
Source: PsyBlog | Psychology Blog - Category: Psychiatry & Psychology Authors: Tags: Brain Health Diabetes subscribers-only Source Type: blogs
Depression, especially in old age, has been consistently associated with increased dementia incidence1,2, though it is still unclear whether depression is a risk or causal factor for dementia or merely a presenting symptom3. The evidence on the relationship of depression, and specifically its subtle presentations, with clinical entities that precede dementia, namely cognitive decline and mild cognitive impairment (MCI), is less consistent, with the majority of evidence indicating that depression and depression symptoms predict incident MCI4,5 and faster cognitive decline6.
Source: The American Journal of Geriatric Psychiatry - Category: Geriatrics Authors: Tags: Regular Research Article Source Type: research
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Conclusions/interpretationIn older adults with type 2 diabetes, long-term adiposity may have a detrimental impact on volume of brain regions relevant to cognitive functioning. Further studies to identify the underlying mechanisms are warranted.Graphical abstract
Source: Diabetologia - Category: Endocrinology Source Type: research
In conclusion, it remains unclear if brain-specific regional and temporal changes occur in the expression of the different APP variants during AD progression. Since APP is also found in blood cells, assessing the changes in APP mRNA expression in peripheral blood cells from AD patients has been considering an alternative. However, again the quantification of APP mRNA in peripheral blood cells has generated controversial results. Brain APP protein has been analyzed in only a few studies, probably as it is difficult to interpret the complex pattern of APP variants and fragments. We previously characterized the soluabl...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Indeed, the science now suggests that inflammation is the single biggest risk factor for serious health problems such as type 2 diabetes, heart disease, arthritis and dementia.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Those with type 2 diabetes had an increased chance of developing vascular dementia in a large observational study.Medscape Medical News
Source: Medscape Diabetes Headlines - Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news
WEDNESDAY, Sept. 23, 2020 -- For older adults with type 2 diabetes, cognitive decline is slower and dementia risk reduced for those receiving metformin, according to a study published online Sept. 23 in Diabetes Care. Katherine Samaras, M.B.B.S.,...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
I recently collaborated on a review paper covering the history of clinical work on upregulation of nicotinamide adenine dinucleotide (NAD) as an approach to therapy. This is of interest to the aging research community because NAD is important to mitochondrial function. NAD levels diminish with age, alongside a loss of mitochondrial function that is known to contribute to the onset and progression of many age-related conditions. Animal studies and a few clinical trials have indicated that increased NAD levels may improve, for example, cardiovascular function in older individuals, as a result of improved mitochondrial functi...
Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
More News: Dementia | Diabetes | Diabetes Type 2 | Endocrinology | Pharmaceuticals | Study