Infection prevention and control and preparedness for COVID-19 in healthcare settings, ECDC (Fifth Update - 6th October 2020)

Key messages Healthcare facilities, including long-term care facilities (LTCFs), should apply several types of measures to minimise the risk of transmission of COVID-19. The mainstays of infection prevention and control (IPC) in all healthcare facilities are administrative measures, physical distancing, hand hygiene and the appropriate use of personal protective equipment (PPE). Administrative measures decrease the opportunities for transmission within healthcare facilities and diminish the risk of outbreaks. In areas with community transmission of COVID-19, staff, visitors and patients should apply physical distancing, hand hygiene and respiratory hygiene, and wear face masks when physical distancing is not possible. Healthcare facilities should ensure that PPE is available and appropriately used to safeguard those providing patient and resident care. In areas with community transmission of COVID-19, frontline healthcare workers should wear medical face masks when caring for patients or residents during all routine activities. Gloves and gowns are recommended when there is a risk of exposure to body fluids and in settings in which contamination is presumed to be high, such as where aerosol-generating procedures are performed. When used, gloves and gowns should always be changed after each patient contact. COVID-19 cases can be released from isolation after consideration of the time from onset of symptoms, the severity of the disease, possible deficiencies of the immune syste...
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news

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Authors: Sinclair G, Johnstone P, Hatiboglu MA Abstract Up until, June 13, 2020,>7,500,000 cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and>400,000 deaths, across 216 countries, have been confirmed by the World Health Organization (WHO). With reference to the two previous beta-CoV outbreaks (SARS-CoV and middle east respiratory syndrome [MERS]), this paper examines the pathophysiological and clinical similarities seen across all three CoVs, with a special interest in the neuroinvasive capability and subsequent consequences for patients with primary or metastatic brain tumors. More wid...
Source: Surgical Neurology International - Category: Neurosurgery Tags: Surg Neurol Int Source Type: research
This article aims to present the first cohort of COVID-19 patients updated to Feb 28th, 2020 in Vietnam and sharing the national response to the pandemic. PMID: 33029087 [PubMed - in process]
Source: International Journal of Medical Sciences - Category: Biomedical Science Tags: Int J Med Sci Source Type: research
Authors: Schwartz RA, Sharma A, Szepietowski JC, Sandhu S, Goldust M Abstract Early December 2019 witnessed an international outbreak of a novel coronavirus (COVID 19) designated severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2). Since then, a number of therapeutic molecules have been explored to have potential efficacy against the SARS-Cov-2 per se or its sequelae. There are no Food and Drug Administration specific therapies approved so far; however, numerous drugs based on varying levels of evidence, in vitro studies and compassionate drug trials are being established as therapeutic agents, especially ...
Source: Journal of Drugs in Dermatology - Category: Dermatology Tags: J Drugs Dermatol Source Type: research
Abstract There is increasing evidence that children and adolescents can efficiently transmit SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19) (1-3). During July-August 2020, four state health departments and CDC investigated a COVID-19 outbreak that occurred during a 3-week family gathering of five households in which an adolescent aged 13 years was the index and suspected primary patient; 11 subsequent cases occurred. PMID: 33031365 [PubMed - indexed for MEDLINE]
Source: MMWR Morb Mortal Wkl... - Category: Epidemiology Authors: Tags: MMWR Morb Mortal Wkly Rep Source Type: research
Molecules, Vol. 25, Pages 4597: NMR as a “Gold Standard” Method in Drug Design and Discovery Molecules doi: 10.3390/molecules25204597 Authors: Emwas Szczepski Poulson Chandra McKay Dhahri Alahmari Jaremko Lachowicz Jaremko Studying disease models at the molecular level is vital for drug development in order to improve treatment and prevent a wide range of human pathologies. Microbial infections are still a major challenge because pathogens rapidly and continually evolve developing drug resistance. Cancer cells also change genetically, and current therapeutic techniques may be...
Source: Molecules - Category: Chemistry Authors: Tags: Review Source Type: research
Coronavirus (CoV) outbreaks have recently emerged as a global public health threat due to their exceptional zoonotic potential — a feature arising from their ability to infect a diverse range of potential hosts combined with their high capacity for mutation and recombination. After Severe Acute Respiratory Syndrome (SARS) CoV-1 in 2003 and Middle East Respiratory Syndrome (MERS) CoV in 2012, with the current SARS-CoV-2 pandemic we are now in the midst of the third deadly international CoV outbreak in less than 20 years. Coronavirus outbreaks present a critical threat to global public health and an urgent necessity fo...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Abstract The inter-cities mobility network is of great importance in understanding outbreaks, especially in Brazil, a continental-dimension country. We adopt the data from the Brazilian Ministry of Health and the terrestrial flow of people between cities from the Brazilian Institute of Geography and Statistics database in two scales: cities from Brazil, without the North region, and from the São Paulo State. Grounded on the complex networks approach, and considering that the mobility network serves as a proxy for the SARS-CoV-2 spreading, the nodes and edges represent cities and flows, respectively. Network...
Source: Cadernos de Saude Publica - Category: International Medicine & Public Health Authors: Tags: Cad Saude Publica Source Type: research
OBJECTIVES: Following the outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus and the subsequent global spread of the 2019 novel coronavirus disease (COVID-19), health systems and the populations who use them have faced unpre...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
By Dr. Stephen A. Berger   Cynomolgus monkey, a known reservoir of the Monkeypox virus   WHAT IS MONKEYPOX? Monkeypox, as the name implies, is a disease of monkeys (unlike chickenpox – which has no relation to chickens). Although the condition is reported in a group of eleven African countries, the virus was first discovered in a laboratory in Denmark in 1958, when it was first isolated from cynomolgus monkeys. The signs and symptoms are similar to those of smallpox. Following a three-day prodrome of fever, headache, myalgia, and back pain, patients develop a papular rash in the face, extremities, and genit...
Source: GIDEON blog - Category: Databases & Libraries Authors: Tags: Epidemiology News Source Type: blogs
CONCLUSIONS: Systems-level interventions may alleviate distress for most providers without the need for specialized mental health intervention. Psychotherapeutic support and referral to specialty care should be available to health workers with severe and intense adverse psychological outcomes during and beyond the COVID-19 pandemic. Evidence-based interventions are urgently needed to better serve health workers both during and following epidemics/pandemics. PMID: 33019857 [PubMed - as supplied by publisher]
Source: Psychiatric Services - Category: Psychiatry Tags: Psychiatr Serv Source Type: research
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