Relation between COVID-19 and Guillain-Barré syndrome in adults: A systematic review

Publication date: Available online 8 October 2020Source: Neurología (English Edition)Author(s): LM Trujillo Gittermann, SN Valenzuela Feris, A von Oetinger Giacoman
Source: Neurologia - Category: Neurology Source Type: research

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Publication date: Available online 8 October 2020Source: Neurophysiologie CliniqueAuthor(s): Céline Tard, Claude-Alain Maurage, Andre Maues de Paula, François Cassim, Arnaud Delval, Grégory Kuchcinski, Jean-Baptiste Davion, Luc Defebvre, Mohammed Bouchiba, Intensive Care Unit Medical Group, Mercedes Jourdain, Joseph Boucraut
Source: Neurophysiologie Clinique - Category: Neuroscience Source Type: research
AbstractObjectivesEvidences from either small series or spontaneous reporting are accumulating that SARS-CoV-2 involves the Nervous Systems. The aim of this study is to provide an extensive overview on the major neurological complications in a large cohort of COVID-19 patients.MethodsRetrospective, observational analysis on all COVID-19 patients admitted from February 23rd to April 30th, 2020 to ASST Papa Giovanni XXIII, Bergamo, Italy for whom a neurological consultation/neurophysiological assessment/neuroradiologic investigation was requested. Each identified neurologic complication was then classified into main neurolog...
Source: Journal of Neurology - Category: Neurology Source Type: research
In conclusion, our study suggests that SARS-CoV-2 antibodies need to be searched in the serum and CSF in patients with GBS living in endemic areas, even in the absence of a clinically severe COVID- 19 infection, and that IL-8 pathway can be relevant in Si-GBS pathogenesis. Further studies are needed to conclude on the relevance of the genetic findings, but it is likely that HLA plays a role in this setting as in other autoimmune neurological syndromes, including those triggered by infections.
Source: Neurological Sciences - Category: Neurology Source Type: research
We thank to Pietro D L et al for their comments on our recently published article (Kilic et al., 2020). In previous studies, viral infections have been reported to have an important role in the etiology of sudden sensorineural hearing loss (SSNHL) (Cohen et al., 2014). Therefore, it is not unreasonable to think that COVID-19, as a viral infection, may also cause SSNHL. Moreover, recently, studies on the effects of SARS-CoV-2 virus on central and peripheral nervous systems have been published. Some of these studies have reported Guillain – Barré syndrome (Toscano et al., 2020) and impaired olfactory function (E...
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: Letter to the Editor Source Type: research
Wondering when to get your flu shot? The best time is before influenza (flu) starts circulating widely. For most people, September or October is ideal for protection through the whole flu season, as the immune response from the vaccine wanes over time. And while changes and restrictions due to COVID-19 may make getting a flu vaccine less convenient for some this year, the pandemic makes it more important than ever. Why do I need to get a flu vaccine yearly? Influenza A and Influenza B cause most cases of flu in humans. Both have many strains that constantly change, accumulating genetic mutations that disguise them from the...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Cold and Flu Coronavirus and COVID-19 Vaccines Source Type: blogs
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cases were first reported in Wuhan, Hubei province of China in December, 2019. SARS- COV-2 primarily affects the cardio-respiratory system. Over the last few months, several studies have described various neurological sequelae of SARS-COV-2 infection. Neurological complications are more frequent in patients with severe respiratory infections. In this review, we have analyzed the current literature on neuromuscular complications associated with SARS-COV-2 and highlighted possible mechanisms of neuromuscular invasion. We reviewed 11 studies describing 11 cases of G...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
We describe a rare case of post-infective Acute Motor Axonal Neuropathy (AMAN) variant of Guillain-Barr è Syndrome (GBS) associated with myelitis and anti-GD1b positivity after SARS-CoV-2 infection. The patient referred to the hospital reporting a history of ten days lasting moderate fever, myalgia and anosmia, with the onset of progressive quadriparesis and ascending paraesthesias in the four limbs since five days from defervescence. A chest computed tomography demonstrated interstitial pneumonia with “ground glass opacities”, suggesting Coronavirus disease (COVID-19). The patient exhibited three negati...
Source: Journal of Neurology - Category: Neurology Source Type: research
Globally, more than 12 million people have been infected with COVID −19 infection till date with more than 500,000 fatalities. Although, Covid-19 commonly presents with marked respiratory symptoms in the form of cough and dyspnoea, a neurotropic presentation has been described of late as well.
Source: The American Journal of Emergency Medicine - Category: Emergency Medicine Authors: Source Type: research
Angelo Gemignani The Coronavirus Disease 2019 (COVID-19) outbreak has shocked the whole world with its unexpected rapid spread. The virus responsible for the disease, the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), enters host cells by means of the envelope spike protein, which binds to angiotensin-converting enzyme 2 receptors. These receptors are highly expressed in heart, lungs, respiratory tract epithelium, endothelial cells and brain. Since an increasing body of significant evidence is highlighting a possible neuroinvasion related to SARS-CoV-2, a state of the art on the neurological complication...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Review Source Type: research
We report a case of bifacial weakness with paresthesia, a recognized Guillain-Barré syndrome subtype characterized by rapidly progressive facial weakness and paresthesia without ataxia or other cranial neuropathies, which was temporally associated with antecedent coronavirus 2019 (COVID-19). This case highlights a potentially novel but critically important neurologic association of the COVID-19 disease process. Herein, we detail the clinicoradiologic work-up and diagnosis, clinical course, and multidisciplinary medical management of this patient with COVID-19. This case is illustrative of the increasingly recognized...
Source: American Journal of Neuroradiology - Category: Radiology Authors: Tags: HEAD & amp; NECK Source Type: research
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