Gradient washout and secondary nephrogenic diabetes insipidus after brain injury in an infant: a case report
ConclusionsGradient washout has not been widely reported in humans, although it has been observed in the mammalian kidneys after prolonged polyuria. Although not a problem with aquaporin protein expression or production, gradient washout causes a different type of secondary nephrogenic diabetes insipidus because the absence of a medullary gradient impairs water reabsorption. We report a case of an infant who developed complex water and sodium imbalances after brain injury. Prolonged polyuria resulting from both water and solute diuresis with low enteral protein intake was thought to cause a urea gradient washout and secondary nephrogenic diabetes insipidus. The restriction of fluid replacements and supplementation of enteral protein appeared adequate to restore the renal osmotic gradient and efficacy of vasopressin.
Authors: Zhang W, Xu JZ, Lu XH, Li H, Wang D, Wang JG Abstract PURPOSE: We hypothesise that dietary sodium intake interacts with serum uric acid to influence blood pressure (BP) in children and adolescents. In the present study, we investigated ambulatory BP in relation to hyperuricaemia, dietary sodium intake and their interaction in children and adolescents with hypertension. MATERIALS AND METHODS: A total of 616 study participants were 10-24 years old and had primary hypertension diagnosed after admission in a specialised inpatient ward. Ambulatory BP monitoring was performed during hospitalisat...
Conclusion: These findings suggest that consumption of peanuts high in oleic acid (D7) may have the potential to delay primary fatty liver symptoms. PMID: 33033472 [PubMed]
CONCLUSION: The proposed PHARMAC criteria will give access to these important drugs to those people with T2DM who will likely benefit the most. PMID: 33032305 [PubMed - in process]
This study investigated the factors associated with the nutritional status of school children in a rural municipality in Cebu, Philippines. Children aged 6-12 years (n = 327) and their parents were asked to participate. Children's anthropometric measurements were taken in schools, while interviews and measurements of parents were conducted at home. Children's nutritional status was assessed using height-for-age (HAZ) and weight-for-age (WAZ) z scores, while body mass index (BMI) was used for parents. Children's dietary patterns and physical activity, and household characteristics, such as food insecurity, eating ...
Authors: Siamashvili M, Davis S Abstract INTRODUCTION: Bromocriptine mesylate quick release (QR) is a dopamine D2 receptor agonist and is the only oral, primarily centrally acting drug that can be used for the treatment of adults with type 2 diabetes. AREAS COVERED: The authors describe current recommendations on the use of bromocriptine mesylate QR. Major efficacy and safety parameters of the late phase trials, including The Cycloset Safety Trial, have been identified and presented. EXPERT OPINION: Efficacy of bromocriptine mesylate QR monotherapy appears to be low but is compensated by favorable safety pr...
Abstract A facile freeze-drying assisted biotemplated route is developed to synthesize Na3V2(PO4)3 embedded in a N-doped three-dimensional mesoporous carbon framework, which has a superior initial discharge capacity and stability for Na-ion batteries. PMID: 33033823 [PubMed]
Publication date: Available online 10 October 2020Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Naila Choudhary, Katia Bravo-Jaimes, Carmen Smotherman, Saadia Sherazi, Dale F. Kraemer, Gladys P. Velarde
Publication date: Available online 9 October 2020Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Vanda Craveiro, Elisabete Ramos, Joana Araújo
Publication date: Available online 9 October 2020Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Elizabeth Sahagun, Brent B. Bachman, Kimberly P. Kinzig
Publication date: Available online 9 October 2020Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Guotao Huang, Xiaoliang Guo, Junxia Guo, Peiyong Zhang, Wanqian Liang, Caiyan Bai, Yongchun Zhang