Oxidative Stress Product, 4-Hydroxy-2-Nonenal, Induces the Release of Tissue Factor-Positive Microvesicles From Perivascular Cells Into Circulation.

CONCLUSIONS: HNE promotes the release of TF+ microvesicles from perivascular cells into the circulation. HNE-induced increased TF activity contributes to intravascular coagulation and inflammation. PMID: 33028097 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/33028097?dopt=Abstract

Source: Arteriosclerosis, Thrombosis and Vascular Biology - October 8, 2020 Category: Cardiology Authors: Ansari SA, Keshava S, Pendurthi UR, Rao LVM Tags: Arterioscler Thromb Vasc Biol Source Type: research