Coronary Vascular Function and Cardiomyocyte Injury: A Report WISE-CVD.

CONCLUSIONS: Our findings indicate that higher u-hscTnI is associated with coronary vascular dysfunction in women with INOCA. This suggests that ischemic cardiomyocyte injury in the setting of coronary vascular dysfunction has the potential to contribute to adverse cardiovascular outcomes observed in these women. Additional studies are needed to confirm and investigate mechanisms underlying these findings in INOCA. REGISTRATION: URL: https://www.clinicaltrials.gov; Unique identifier: NCT00832702. PMID: 33028098 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/33028098?dopt=Abstract

Source: Arteriosclerosis, Thrombosis and Vascular Biology - October 8, 2020 Category: Cardiology Authors: AlBadri A, Wei J, Quesada O, Mehta PK, Xiao Y, Ko YA, Anderson RD, Petersen J, Azarbal B, Samuels B, Henry TD, Cook-Wiens G, Handberg EM, Van Eyk J, Pepine CJ, Bairey Merz CN Tags: Arterioscler Thromb Vasc Biol Source Type: research