Impact of T Cell Repertoire Diversity on Mortality Following Cord Blood Transplantation

ConclusionsUsing a fast high-throughput TCR sequencing assay we have demonstrated that high TCR diversity is associated with better patient outcomes following CBT. Importantly, this assay is easily performed on posttransplant PB samples, even as early as day 28 posttransplant, making it an excellent candidate for early identification of patients at high risk of death.

Source: Frontiers in Oncology - October 9, 2020 Category: Cancer & Oncology Source Type: research