Nursing role in the assessment and care of hepatic sinusoidal obstruction syndrome patients: a consensus paper by the “Gruppo Italiano Trapianto di Midollo Osseo”

ConclusionSOS is relatively rare; therefore, a holistic approach to the patients ’ needs considering nursing role as essential may result in better care outcomes.
Source: Supportive Care in Cancer - Category: Cancer & Oncology Source Type: research

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ven Hodgkin lymphoma (HL) is a B-cell malignancy representing approximately one in ten lymphomas diagnosed in the United States annually. The majority of patients with HL can be cured with chemotherapy; however, 5–10% will have refractory disease to front-line therapy and 10–30% will relapse. For those with relapsed or refractory (r/r) HL, salvage chemotherapy followed by autologous stem cell transplant (ASCT) is standard of care, but half of patients will subsequently have disease progression. Relapse following ASCT has been associated with exceedingly poor prognosis with a median survival of only ...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Review Source Type: research
The thymus is a small organ in which thymocytes generated in the bone marrow mature to become T cells of the adaptive immune system. Unfortunately, the thymus atrophies with age, its active tissue largely replaced by fat in most people by age 50 or so. Thereafter the adaptive immune system declines into immunosenescence and inflammaging, deprived of a sufficiently large supply of reinforcement cells. Given the importance of the immune system to health, in matters including tissue maintenance, resistance to infection, suppression of cancer, and more, regeneration of the thymus must be an important component of any serious e...
Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
(Medical University of South Carolina) With more than $1.5 million in funding from the National Cancer Institute, MUSC Hollings Cancer Center researchers discovered a new biomarker, plasmacytoid dendritic cells expressing the ICOS ligand, whose activity can be blocked by the dual-acting drug candidate ALPN-101 to prevent graft-versus-host disease following hematopoietic stem cell transplantation.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news
Blood Cancer Journal, Published online: 06 October 2020; doi:10.1038/s41408-020-00361-8CPX-351 treatment in secondary acute myeloblastic leukemia is effective and improves the feasibility of allogeneic stem cell transplantation: results of the Italian compassionate use program
Source: Blood Cancer Journal - Category: Hematology Authors: Source Type: research
This article has been retracted. Please see the retraction notice for more detail: https://doi.org/10.1007/s00520-020-05770-w.
Source: Supportive Care in Cancer - Category: Cancer & Oncology Source Type: research
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
de Masson Cutaneous T-cell lymphomas (CTCLs) are non-Hodgkin lymphomas that develop primarily in the skin. They account for almost 80% of primary cutaneous lymphomas. Epidermotropic CTCLs (mycosis fungoides (MF) and Sézary syndrome (SS)) are the most common form of CTCL. The course of the disease ranges from an indolent clinical behavior in early-stage disease to an aggressive evolution in the advanced stages. Advanced-stage disease is defined by the presence of tumors, erythroderma, or significant blood, nodal or visceral involvement. Advanced-stage disease is characterized by frequent disease relapses, re...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Review Source Type: research
Post-transplant lymphoproliferative disorders are comprised of lymphoid or plasmacytic proliferations that develop because of immunosuppression following solid organ, bone marrow, or stem cell allotransplant 1 2 . Vast majority of PTLDs are associated with the EBV infection and constitute EBV-driven polyclonal or monoclonal B-cell or T-cell proliferations 3. There are four major subtypes of PTLDs (according to WHO 2016) – non-destructive PTLDs, monomorphic, polymorphic and classic Hodgkin lymphoma.
Source: Cancer Genetics and Cytogenetics - Category: Genetics & Stem Cells Authors: Source Type: research
Brown, 54, died Tuesday at his home in Palm Springs, CA. His first stem cell transplant in 2007 was only partly successful, but a second transplant from the same donor in 2008 seemed to rid him of HIV.Associated Press
Source: Medscape Transplantation Headlines - Category: Transplant Surgery Tags: HIV/AIDS News Source Type: news
Conclusions: The significance of the most prominent cell type in normal breast stroma, the fibroblast, in directingepithelial differentiation is largely unknown. Through establishment of lobular and interlobular fibroblast cell lines,we here demonstrate that epithelial progenitors are submitted to stromal cues for site-specific differentiation. Ourfindings lend credence to considering stromal subtleties of crucial importance in the development of normal breastand, in turn, breast cancer.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
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