Impact of primary tumor location on survival after curative resection in patients with colon cancer: A meta-analysis of propensity score-matching studies.

CONCLUSION: This meta-analysis has demonstrated that there was no significant difference in 5-year OS between patients with RSCC and those with LSCC after curative resection.
IMPLICATIONS FOR PRACTICE: The aim of this study is to explore the impact of primary tumor location (PTL) on survival after curative surgery for colon cancer (CC) patients using propensity score-matching (PSM) studies. To integrate the impact of PTL on 5-year overall survival (OS) after curative surgery, a meta-analysis was performed for the selected PSM studies. Five studies involving a total of 398,687 CC patients were included in this meta-analysis. Among 205,641 Right-sided CC (RSCC) patients, 69,091 (33.6%) died during the observation period, whereas among 193,046 Left-sided CC (LSCC) patients, 63,380 (32.8%) died during the same period. These results revealed that RSCC patients and LSCC patients had almost the same 5-year OS (RR, 0.98; 95% CI, 0.89 - 1.07; P = 0.64; I2 = 97%). This meta-analysis has demonstrated that there was no significant difference in 5-year OS between patients with RSCC and those with LSCC after curative resection.
PMID: 33031622 [PubMed - as supplied by publisher]

Source: The Oncologist - October 8, 2020 Category: Cancer & Oncology Authors: Ishizuka M, Shimizu T, Shibuya N, Takagi K, Hachiya H, Nishi Y, Suda K, Aoki T, Kubota K Tags: Oncologist Source Type: research