Mitochondrial Ejection for Cardiac Protection: The Macrophage Connection.

Mitochondrial Ejection for Cardiac Protection: The Macrophage Connection. Cell Metab. 2020 Oct 06;32(4):512-513 Authors: Bartelt A, Weber C Abstract Mitochondrial dysfunction is a hallmark of heart disease. Nicolás-Ávila et al. (2020) now find that cardiomyocytes eject dysfunctional mitochondria in exopher vesicles, which require elimination by specialized heart-resident macrophages, altogether supporting proper heart function. PMID: 33027673 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/33027673?dopt=Abstract

Source: Cell Metabolism - October 6, 2020 Category: Cytology Authors: Bartelt A, Weber C Tags: Cell Metab Source Type: research