Effects of Ginger on clinical manifestations and paraclinical features of patients with Severe Acute Respiratory Syndrome due to COVID-19: A structured summary of a study protocol for a randomized controlled trial

AbstractObjectivesWe investigate the effects of Ginger, compared to the usual therapeutic regimen on clinical manifestations and paraclinical features in patients with confirmed COVID-19 that are moderately ill.Trial designThis is a single center, randomized, double-blind, placebo-controlled clinical trial with parallel group design.ParticipantsInclusion criteria:1. Patients admitted to Severe Acute Respiratory Syndrome (SARS) Departments at Shahid Mohammadi Hospital, Bandar Abbas, Iran2. Age ≥18 years (weight ≥35 kg)3. Hospitalized ≤48 hours4. Confirmed SARS-CoV-2 diagnosis (Positive polymerase chain reaction (PCR))5. Moderate pneumonia and lung involvement in imaging6. Signing informed consent and willingness of study participant to accept randomization to any assigned treatment armExclusion criteria:1. Underlying diseases, including heart disease, chronic hypertension, severe renal failure, severe liver failure, and thyroid disorders2. Use of warfarin, selective serotonin reuptake inhibitors (SSRIs), monoamine oxidase inhibitors (MAOIs), diuretics, corticosteroids, and antiarrhythmic drugs3. Severe and critical pneumonia4. History of known allergy to Ginger5. Pregnancy and breastfeedingIntervention and comparatorIntervention group: The standard treatment regimen for COVID-19 along with Ginger-based herbal tablets (Vomigone ®, Dineh Pharmaceutical Company, Iran) at a dose of 1000 mg three times a day for a period of seven days.Control group: The standard treatm...
Source: Trials - Category: Research Source Type: clinical trials

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Source: Expert Review of Anti-Infective Therapy - Category: Infectious Diseases Tags: Expert Rev Anti Infect Ther Source Type: research
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Source: Blood Pressure - Category: Hematology Tags: Blood Press Source Type: research
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Source: Blood Pressure - Category: Hematology Tags: Blood Press Source Type: research
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Source: Expert Review of Gastroenterology and Hepatology - Category: Gastroenterology Tags: Expert Rev Gastroenterol Hepatol Source Type: research
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Source: Journal of Pregnancy - Category: OBGYN Tags: J Pregnancy Source Type: research
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Source: Journal of Pregnancy - Category: OBGYN Tags: J Pregnancy Source Type: research
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