Impact of hematologic malignancy and type of cancer therapy on COVID-19 severity and mortality: lessons from a large population-based registry study

Patients with cancer have been shown to have a higher risk of clinical severity and mortality compared to non-cancer patients with COVID-19. Patients with hematologic malignancies typically are known to have h...
Source: Journal of Hematology and Oncology - Category: Hematology Authors: Tags: Research Source Type: research

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Telemedicine has historically been underutilized in medicine broadly, and specifically in oncology, despite the general availability of the needed infrastructure to offer it as a platform for remote care. The COVID-19 pandemic posed new risks of infection exposure and potentially life-threatening complications, particularly in patients with cancer, created a new setting for cancer care ideally suited for the rapid roll-out of telemedicine for patients with cancer who need regular follow up but in whom live visits may not be critical. In the months since the upheaval of our health care system and wider society in the United...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
Shagun Bhatia Shah, Rajiv ChawlaSaudi Journal of Anaesthesia 2020 14(4):504-509 Humanity is witnessing an unprecedented tsunami of corona virus disease 2019 (COVID-19) patients. Till date, India houses 10,453 confirmed COVID-19 patients with a death toll of 358 nationwide and the number is steadily rising with each passing day. The capital city of Delhi, harbouring 1510 patients, has the dubious distinction of being the second largest hotspot for COVID positive patients in India, second only to the state of Maharashtra. Being immuno-compromised, cancer patients are first more susceptible to catch this virus and secondly m...
Source: Saudi Journal of Anaesthesia - Category: Anesthesiology Authors: Source Type: research
TUESDAY, Sept. 22, 2020 -- People with cancer are at increased risk for severe COVID-19. Now, a preliminary study suggests that certain cancer therapies may heighten those odds even further. Researchers found that of 3,600 U.S. cancer patients who...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
Before the pandemic, about 1,000 new patients came to Boston’s Dana-Farber Cancer Institute for treatment consultations each week. When COVID-19 hit Massachusetts this spring, the number of new consultations fell by half and the hospital moved as many appointments as possible online. Now, with daily case counts relatively low in the area, the hospital is back to scheduling about 800 consultations per week, using a mixture of telemedicine and in-person appointments, says associate chief medical officer Dr. Andrew Wagner—but that still means about 200 cancer patients per week are not getting the treatment consult...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 Source Type: news
We report that electrical stimulation (ES) stimulation of post-stroke aged rats led to an improved functional recovery of spatial long-term memory (T-maze), but not on the rotating pole or the inclined plane, both tests requiring complex sensorimotor skills. Surprisingly, ES had a detrimental effect on the asymmetric sensorimotor deficit. Histologically, there was a robust increase in the number of doublecortin-positive cells in the dentate gyrus and SVZ of the infarcted hemisphere and the presence of a considerable number of neurons expressing tubulin beta III in the infarcted area. Among the genes that were unique...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Sheila N Myatra, Sushan Gupta, Prathamesh S PaiJournal of Anaesthesiology Clinical Pharmacology 2020 36(5):96-104 The severe acute respiratory syndrome corona virus 2(SARS-Cov2) virus replicates in the nasal cavity, nasopharynx, and the oropharynx. During oral surgery, the risk of viral transmission is high during instrumentation in these areas, while performing airway management procedures, the oral surgery itself, and related procedures. During the corona virus disease 2019 (COVID-19) pandemic, patients with an oral pathology usually present for emergency procedures. However, patients with oral cancer, being a semi-emer...
Source: Journal of Anaesthesiology Clinical Pharmacology - Category: Anesthesiology Authors: Source Type: research
This observational study of cancer patients diagnosed with Covid-19 (n=890; 218 in the UK) found no evidence that receipt of anti-cancer therapy (chemotherapy, targeted therapy, endocrine therapy and immunotherapy) was associated with mortality.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
Abstract It is well established that Escherichia coli represents a powerful tool for the over-expression of human proteins for structure/function studies. In many cases, such as for membrane transporters, the bacterial toxicity or the aggregation of the target protein hamper the expression limiting the application of this tool. The aim of this study was finding the appropriate conditions for the expression of reluctant proteins that is the human neutral amino acid transporters ASCT2 and B0AT1, that have great relevance to human health in cancer therapy and in COVID-19 research, respectively. The cDNAs coding for t...
Source: Molecular Biology Reports - Category: Molecular Biology Authors: Tags: Mol Biol Rep Source Type: research
AbstractCancer patients are at particular risk from COVID-19 since they usually present multiple risk factors for this infection such as older age, immunosuppressed state, comorbidities (e.g., chronic lung disease, diabetes, cardiovascular diseases), need of frequent hospital admissions and visits. Therefore, in the COVID era, oncologists should carefully weigh risks/benefits when planning cancer therapies and follow-up appointments. Recently, several scientific associations developed specific guidelines or recommendations to help physicians in their clinical practice. This review focuses on main available guidelines/recom...
Source: Medical Oncology - Category: Cancer & Oncology Source Type: research
Conclusion: This study will provide comprehensive evidence for medical staff to adopt effective treatment strategies for breast cancer patients during the COVID-19 pandemic. PROSPERO registration number: CRD42020188208.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research
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