Biochemical characterization of extracellular fructosyltransferase from Aspergillus oryzae IPT-301 immobilized on silica gel for the production of fructooligosaccharides.

CONCLUSION: These results suggest a high potential of application of silica gel as support for FTase immobilization aiming at FOS production. PMID: 33025334 [PubMed - as supplied by publisher]
Source: Biotechnology Letters - Category: Biotechnology Authors: Tags: Biotechnol Lett Source Type: research

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Publication date: March 2021Source: Food Control, Volume 121Author(s): Hongbo Li, Xiaofeng Kang, Shan Wang, Haizhen Mo, Dan Xu, Wei Zhou, Liangbin Hu
Source: Food Control - Category: Food Science Source Type: research
A 69-year-old man with newly diagnosed B-precursor acute lymphoblastic leukemia (B-ALL) had impaired consciousness (Glasgow coma scale [GCS] E4V4M6) on day 24 of remission induction therapy. Serum beta-D-glucan (61.0  pg/μL) and Aspergillus galactomannan antigens in the serum and cerebrospinal fluid (CSF) (both ≥5.0) were elevated. Computed tomography showed a nodule in the left lung. Magnetic resonance imaging (MRI) revealed multiple brain lesions, and brain biopsy confirmed aspergillosis (Fig. 1) accordin g to the updated invasive fungal disease definition (Donnelly et al., 2019).
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: Medical Imagery Source Type: research
Publication date: November 2020Source: Food Research International, Volume 137Author(s): Rodrigo Lira de Oliveira, Vinícius Luís Vilela dos Santos, Marcos Fellipe da Silva, Tatiana Souza Porto
Source: Food Research International - Category: Food Science Source Type: research
CONCLUSION: The extremely high concentration of yeast extract leads to marked morphological changes of A. terreus and the elimination of (+)-geodin and asterric production, while applying the excess of lactose is stimulatory in terms of lovastatin production. PMID: 33026584 [PubMed - as supplied by publisher]
Source: Biotechnology Letters - Category: Biotechnology Authors: Tags: Biotechnol Lett Source Type: research
, Mateos-Díaz JC Abstract The enzymatic synthesis of alkyl ferulates is an important reaction in cosmetic and pharmaceutical chemistries, since it may allow to expand the biorefinery concept valorizing biomass wastes enriched in ferulic acid. However, robust biocatalysts for that purpose are scarce. Herein, we have immobilized the type A feruloyl esterase from Aspergillus niger (AnFaeA) as cross-linked enzyme aggregates, employing chitosan as co-feeder (ChCLEAs). High immobilization yields and relative activity recovery were attained in all assessed conditions (> 93%). Furthermore, we enhanced the therma...
Source: Applied Microbiology and Biotechnology - Category: Microbiology Authors: Tags: Appl Microbiol Biotechnol Source Type: research
Lv Xie The climate characteristics of the islands in the Nansha Islands of China are a typical marine climate including high temperature, high relative humidity, high salt content, strong solar radiation, and long sunshine. These can provide suitable conditions for mold reproduction on the surface of the wall in a building. Therefore, mildew pollution on the wall for a long time can easily damage the building’s structure. It does not only directly affect the appearance of the building, but also indirectly affects the indoor environment and human health. In this paper, dominant fungi in the residential bui...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
A new polyketide-non-ribosomal peptide hybrid molecule, pyranoviolin A (1), was discovered from the genome-sequenced fungus Aspergillus violaceofuscus CBS 115571 and was characterized to be the first pyranonigrin analog harboring the C-3 methoxy group. Examination of the genome sequence of the fungus identified a putative biosynthetic gene cluster of 1, which was designated as the pyv cluster. The gene deletion experiment of the polyketide synthase (PKS)-non-ribosomal peptide synthetase (NRPS) hybrid gene in the cluster confirmed the involvement of the pyv cluster in the pyranoviolin A biosynthesis. Finally, a plausible bi...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Publication date: December 2020Source: Biochemical Systematics and Ecology, Volume 93Author(s): Zhi-Yong Xu, Xue-Xia Zhang, Jian-Kun Ma, Yong Yang, Jing Zhou, Jing Xu
Source: Biochemical Systematics and Ecology - Category: Biochemistry Source Type: research
Abstract The fungal pathogen Pyrenophora teres f. sp. maculata (Ptm), responsible for spot-form of net blotch (SFNB), is currently the most significant disease of barley in Australia and a major disease worldwide. Management of SFNB relies heavily on fungicides and in Australia the demethylase inhibitors (DMIs) predominate. There have been sporadic reports of resistance to DMIs in Ptm but the mechanisms remain obscure. Ptm isolates collected from 1996 to 2019 in Western Australia were tested for fungicide sensitivity levels. Decreased sensitivity to DMIs was observed in isolates collected after 2015. Resistance fa...
Source: Fungal Genetics and Biology - Category: Biology Authors: Tags: Fungal Genet Biol Source Type: research
Abstract In 1990 the first fungal secondary metabolite biosynthetic gene was cloned in Aspergillus nidulans. Thirty years later,>30 biosynthetic gene clusters (BGCs) have been linked to specific natural products in this one fungal species. While impressive, over half of the BGCs in A. nidulans remain uncharacterized and their compounds structurally and functionally unknown. Here, we provide a comprehensive review of past advances that have enabled A. nidulans to rise to its current status as a natural product powerhouse focusing on the discovery and annotation of secondary metabolite clusters. From genome seque...
Source: Fungal Genetics and Biology - Category: Biology Authors: Tags: Fungal Genet Biol Source Type: research
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