IJERPH, Vol. 17, Pages 7348: Validation and Adaptation of the “Modified Transplant Symptom Occurrence and Symptom Distress Scale” for Kidney Transplant Recipients
IJERPH, Vol. 17, Pages 7348: Validation and Adaptation of the “Modified Transplant Symptom Occurrence and Symptom Distress Scale” for Kidney Transplant Recipients International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197348 Authors: Jisu Kim Insil Jang The aim was to adapt and validate the Modified Transplant Symptom Occurrence and Symptom Distress Scale (MTSOSD-59R) for kidney transplant recipients undergoing immunosuppressive therapy in Korea. The MTSOSD-59R has been used with solid organ transplant recipients globally to assess the adverse effects of immunosuppressive medication. A descriptive cross-sectional design was used. MTSOSD-59R was first translated, and pilot tested. Next, content validity was established with nine organ transplant experts. Then, from October 2017 to October 2018, the Korean MTOSOSD-59R was administered to a convenience sample of 122 kidney transplant recipients recruited from a single center. Ridit analysis was used to measure symptom occurrence and distress. The known-group approach was used to test the construct validity using Mann–Whitney U tests for between-group comparisons. The content validity index for MTSOSD-59R was 0.98, and known-group validity was confirmed. The split-half Spearman–Brown corrected reliability coefficient was 0.902 for symptom occurrence and 0.893 for symptom distress. The four most frequent and distressing symptoms were fatigue, lack of energy, thinnin...
Publication date: Available online 16 May 2020Source: Annals of Medicine and SurgeryAuthor(s): Shakir Saleem Jabali, Zana Sidiq M. Saleem, Ayad Ahmad Mohammed, Newar M. Mahmood
This study investigated the safety of a novel cell-labeling technology with mKATE and Renilla reniformis luciferase (mKATE-renLUC) and assessed the efficacy on tracking implanted human placental stromal cells (PSC) in an erectile dysfunction (ED) animal model. Human PSC were labeled with mKATE-renLUC using a lentivirus. Cell viability, apoptosis, proliferation, migration, surface marker expression and differentiation potential of the labeled PSC were evaluated and compared with non-labeled PSC. The paracrine profile of labeled cells was examined using an angiogenesis protein array. The brightness and duration of labeled ce...
Conclusion: In conclusion, this study showed that treatment with sildena ﬁl in renal allograft recipients with erectile dysfunction is a valid and safe option.Nephron
Low-intensity shockwave therapy for erectile dysfunction in kidney transplant recipients. A prospective, randomized, double blinded, sham-controlled study with evaluation by penile Doppler ultrasonography, Published online: 14 August 2018; doi:10.1038/s41443-018-0062-2Low-intensity shockwave therapy for erectile dysfunction in kidney transplant recipients. A prospective, randomized, double blinded, sham-controlled study with evaluation by penile Doppler ultrasonography
Hormonal changes, in either men or women experiencing chronic kidney disease (CKD), cause a decreased libido, erectile dysfunction, dysmenorrhea and ovarian dysfunction, all of which may contribute to infertility. Patients could rapidly restore endocrines and sexual function after a successful renal transplantation (RTx), which may assist in achieving a successful pregnancy. However, the fetus will be exposed to the immunosuppressive agents passed on from the female recipients, which may be another potential factor leading to a poor fetal outcome.
ConclusionsA quantification of academic and public interest in the urological field is feasible using a novel new media‐based methodology. We found several mismatches in public versus academic interest in urological diseases and treatments, which has implications for research strategies, conference planning and patient information projects. Regular re‐assessments of the public and academic interest landscape can contribute to detecting and proving trends in the field of urology.
In conclusion, we found no association of 25(OH)D concentration with the presence and severity of ED in renal transplant recipients. So far, there are no similar published data. PMID: 29485785 [PubMed - in process]
CONCLUSION: Kidney transplantation improves sexuality and fertility in men and women with chronic kidney disease. PMID: 27665408 [PubMed - as supplied by publisher]
CONCLUSIONS: CKD is frequently associated with an hypogonadism whose correction is validated only in the setting of erectile dysfunction treatment. The other benefits of the correction of hypogonadism in the CKD patients, including overall survival, needs to be evaluated. PMID: 27647650 [PubMed - as supplied by publisher]
AbstractSexual dysfunction is a common finding in both men and women with chronic kidney failure. Common disturbances include erectile dysfunction in men, menstrual abnormalities in women, and decreased libido and fertility in both sexes. These abnormalities are primarily organic in nature and are related to uremia as well as the other comorbid conditions that frequently occur in the chronic kidney failure patient. Fatigue and psycho social factors related to the presence of a chronic disease are also contributory factors. Disturbances in the hypothalamic-pituitary-gonadal axis can be detected prior to the need for dialysi...