Commentary: Complexities upon complexities in cluster-randomized trials: a commentary on incorporating truncation in outcomes

Mwandighaet al. have presented an interesting case and accompanying simulation studies to explore issues of truncation on count data in a cluster randomized setting.1 The results support the notion that researchers planning these complex cluster randomized trials (CRTs) consider exploring the impact of this truncation in sample size and power calculations early on to avoid underpowered studies. Although the overall results are not surprising and can likely be deduced from the theoretical underpinnings, or intuitively for the savvy researcher (i.e. more severe cases of this truncation will result in more severe consequences for power), the magnitude of impact and the particularly vulnerable study scenarios require special attention.
Source: International Journal of Epidemiology - Category: Epidemiology Source Type: research
More News: Epidemiology | Study