Uninterrupted direct oral anticoagulant treatment during acute illness: Impact on clinical outcomes

Uninterrupted drug therapy during acute illness is often associated with pharmacokinetic and pharmacodynamic variations. Among warfarin treated patients, these changes are reflected in the INR. However, in the case of direct oral anticoagulants (DOACs), given that routine laboratory monitoring is not recommended, these changes may result in unforeseen thromboembolic or bleeding events.

Source: Thrombosis Research - October 7, 2020 Category: Hematology Authors: Itai Gueta, Nadav Yehoshua Shacham, Noa Markovits, Hillel Halkin, Ronen Loebstein Source Type: research