Catalyst-Free Decarboxylative Dearomation of Isoquinolines with β-Keto Acids and Sulfonyl Chlorides in Water: Access to Dihydroisoquinoline Derivatives

Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB01799J, PaperYutong Zhang, Fuzhong Han, Jia Lina, Xiang-Ping Hu An efficient and concise catalyst-free one-pot synthetic protocol of dihydroisoquinoline derivatives has been developed by a three-component condensation of isoquinolines with β-keto acids and sulfonyl chlorides. This transformation of decarboxylative... The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Organic and Biomolecular Chemistry - October 8, 2020 Category: Molecular Biology Authors: Yutong Zhang Source Type: research