Use of Noninvasive Scores for Advanced Liver Fibrosis Can Guide the Need for Hepatic Biopsy During Bariatric Procedures

We performed a retrospective review of 2465 patients undergoing routine liver biopsy during a bariatric operation and found a prevalence of advanced fibrosis (stage 3-4) in 3%. Non-invasive risk calculators can potentially screen out advanced fibrosis in one-third of the population.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Tags: Original articles Source Type: research

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Several studies have evaluated the effect of intragastric injection of botulinum toxin A to treat obesity, achieving mixed results. Our objective is to determine the effect of intragastric botulinum toxin A on weight loss, satiety, biomarkers, and quality of life of obese patients prior bariatric surgery.
Source: Clinical Nutrition - Category: Nutrition Authors: Tags: Randomized Control Trials Source Type: research
AbstractPurposeIn patients with obesity, micronutrient deficiencies have been reported both before and after bariatric surgery (BS). Obesity is a chronic pro-inflammatory status, and inflammation increases the risk of micronutrient malnutrition. Our objective was to assess in pre-BS patients the prevalence of micronutrient deficiencies and their correlation with blood values of C-reactive protein (CRP).MethodsAnthropometric data, instrumental examinations, and blood variables were centrally measured in the first 200 patients undergoing a pre-BS evaluation at the “Città della Salute e della Scienza” Hospi...
Source: Journal of Endocrinological Investigation - Category: Endocrinology Source Type: research
Superior mesenteric artery (SMA) syndrome, Wilkie ’s or Cast Syndrome is a rare disease which was first described in 1842. It is seen in patients most often after dramatic weight loss due to starvation, burns, anorexia nervosa, or after bariatric surgery.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Tags: VIDEO CASE REPORT Source Type: research
Conditions:   Morbid Obesity;   Surgery Interventions:   Drug: Ketamine;   Drug: Dexmedetomidine;   Drug: Normal Saline 0.9% Sponsors:   Ain Shams University;   Ministry of Health, Kuwait Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
k G Abstract As of October 2020, the Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2), responsible for Coronavirus Disease 2019 (COVID-19), has infected over 33million individuals and killed over one million people worldwide. (https://coronavirus.jhu.edu/map.html accessed October 1 2020) Obesity and its complications are linked to severe forms of COVID-19, favouring an increased hospitalization and mortality rate. Despite being the gold-standard for the treatment of selected individuals with severe obesity, there is scarce information on whether or not bariatric surgery modifies the prognosis of people...
Source: Obesity - Category: Eating Disorders & Weight Management Authors: Tags: Obesity (Silver Spring) Source Type: research
Current obesity treatment strategies include diet, exercise, bariatric surgery, and a limited but growing repertoire of medications. Individual weight loss in response to each of these strategies is highly variable. Here we review research into factors potentially contributing to inter-individual variability in response to treatments for obesity, with a focus on studies in humans. Well-recognized factors associated with weight loss capacity include diet adherence, physical activity, sex, age, and specific medications.
Source: Metabolism - Clinical and Experimental - Category: Biomedical Science Authors: Source Type: research
SummarySocial support is important to optimize bariatric surgery outcomes, but limited tools exist for brief and effective assessment preoperatively. The aims of the study were to determine the extent to which two ratings of social support can predict bariatric surgery outcomes, and to examine any associations between these two methods.In this retrospective study, patients were included for whom the Cleveland clinic behavioral rating system (CCBRS) and Flanagan quality of life scale (FQoLS) scores were obtained as part of their preoperative psychosocial evaluation. They were followed up for 6 to 24  months after bar...
Source: Clinical Obesity - Category: Eating Disorders & Weight Management Authors: Tags: Original Research Article Source Type: research
Although metabolic syndrome (MetS) in children and adolescents is a frequently discussed topic in the literature, uniform guidelines on its definition and treatment are still lacking. Insulin resistance, central obesity, dyslipidaemia, and hypertension are commonly considered the main components of MetS. The first recommended approach to all these pathological conditions in children and adolescents is lifestyle intervention (diet and physical exercise); however, in some selected cases, a pharmacological or surgical treatment might prove useful for the prevention of metabolic and cardiovascular complications. The aim of thi...
Source: Hormone Research in Paediatrics - Category: Endocrinology Source Type: research
Authors: Boru CE, Termine P, Antypas P, Iossa A, Ciccioriccio MC, De Angelis F, Micalizzi A, Silecchia G Abstract BACKGROUND: Hiatal hernia repair (HHR) is still controversial during bariatric procedures, especially in case of laparoscopic sleeve gastrectomy (LSG). AIMS: to report the long-term results of concomitant HHR, evaluating the safety and efficacy of posterior cruroplasty (PC), simple or reinforced with biosynthetic, absorbable Bio-A® mesh (Gore, USA). Primary endpoint: PC's failure, defined as symptomatic HH recurrence, nonresponding to medical treatment and requiring revisional surgery. METHO...
Source: Minerva Chirurgica - Category: Surgery Tags: Minerva Chir Source Type: research
Condition:   Pediatric Obesity Interventions:   Drug: Topiramate;   Drug: Phentermine Sponsors:   Janey Pratt;   Maternal and Child Health Research Institute Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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