Benefits of bariatric surgery prior to SARS CoV 2 infection in modulating the response to COVID-19.
Benefits of bariatric surgery prior to SARS CoV 2 infection in modulating the response to COVID-19. Obesity (Silver Spring). 2020 Oct 06;: Authors: Landecho MMF, Frühbeck G Abstract As of October 2020, the Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2), responsible for Coronavirus Disease 2019 (COVID-19), has infected over 33million individuals and killed over one million people worldwide. (https://coronavirus.jhu.edu/map.html accessed October 1 2020) Obesity and its complications are linked to severe forms of COVID-19, favouring an increased hospitalization and mortality rate. Despite being the gold-standard for the treatment of selected individuals with severe obesity, there is scarce information on whether or not bariatric surgery modifies the prognosis of people living with obesity in the current COVID-19 pandemic. Bel Lassen and colleagues have carried out the first study with a high number of patients in their sample, bringing light into this area of uncertainty. The authors provide evidence of the importance of diabetes itself as a risk factor for severe COVID-19. PMID: 33021051 [PubMed - as supplied by publisher]
CONCLUSION: A combination of underlying chronic conditions such as hypertension, obesity, and cardiovascular diseases together with altered ACE receptor expression, immune dysregulation via cytokine storm, alveolar and endothelial dysfunction, increased systemic coagulation may put individuals with diabetes at risk for COVID-19 severity. More studies are needed to elucidate how glucose-lowering drugs may modulate the host immune response in diabetic individuals, especially following the administration of potential COVID-19 vaccines.PMID:34365925 | DOI:10.2174/1573399817666210806104349
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV2) is a novel coronavirus emerging from Wuhan, China that can cause severe respiratory illness and a myriad of other complications that is now known as COVID-19. This disease was declared a pandemic by World Health Organization in March 2020 and has affected hundreds of millions of people worldwide1. COVID-19 clinical presentations can vary greatly between patients and those who are at highest risk for severe illness leading to hospitalization and/or death include older age, obesity, diabetes, and immunocompromised state, amongst other conditions2.
Nutr Hosp. 2021 Jun 28. doi: 10.20960/nh.03469. Online ahead of print.ABSTRACTINTRODUCTION: coronavirus disease 2019 (COVID-19) encompasses a wide spectrum of symptoms, including respiratory, gastrointestinal, hematological, and dermatological manifestations. The virus interaction with cells located in the respiratory tract causes the release of inflammatory mediators, whose involvement could be exacerbated by co-existing obesity, diabetes, and cardiovascular events.OBJECTIVES: the objective of this research was to analyze the clinically metabolic status in patients who have suffered COVID-19 disease in order to predict th...
Arch Cardiovasc Dis. 2021 Mar 2:S1875-2136(21)00049-8. doi: 10.1016/j.acvd.2021.01.003. Online ahead of print.ABSTRACTBACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic has led to a public health crisis. Only limited data are available on the characteristics and outcomes of patients hospitalized for COVID-19 in France.AIMS: To investigate the characteristics, cardiovascular complications and outcomes of patients hospitalized for COVID-19 in France.METHODS: The Critical COVID-19 France (CCF) study is a French nationwide study including all consecutive adults with a diagnosis of severe acute respiratory syndrome co...