Circular RNA as a potential diagnostic and/or therapeutic target for endometriosis.

Circular RNA as a potential diagnostic and/or therapeutic target for endometriosis. Biomark Med. 2020 Sep;14(13):1277-1287 Authors: Dana PM, Taghavipour M, Mirzaei H, Yousefi B, Moazzami B, Chaichian S, Asemi Z Abstract Endometriosis is a pathology form of endometrium that behaves in a similar way to malignancies, such as invasion and resistance to apoptosis. Circular RNAs (CircRNAs) are a class of noncoding RNAs that have several biological functions including, miRNA sponging, sequestering of proteins, enhancing parental gene expression and translation resulting in polypeptides. In this review, we highlighted the roles of circRNAs as potential diagnostic and therapeutic biomarkers in endometriosis. Moreover, we summarized the roles of circRNAs in the pathogenesis of endometriosis via different signaling pathways, such as the miRNA network and apoptosis. PMID: 33021386 [PubMed - as supplied by publisher]
Source: Future Medicine: Biomarkers in Medicine - Category: Internal Medicine Tags: Biomark Med Source Type: research