Pre-operative micronutrient deficiencies in patients with severe obesity candidates for bariatric surgery

AbstractPurposeIn patients with obesity, micronutrient deficiencies have been reported both before and after bariatric surgery (BS). Obesity is a chronic pro-inflammatory status, and inflammation increases the risk of micronutrient malnutrition. Our objective was to assess in pre-BS patients the prevalence of micronutrient deficiencies and their correlation with blood values of C-reactive protein (CRP).MethodsAnthropometric data, instrumental examinations, and blood variables were centrally measured in the first 200 patients undergoing a pre-BS evaluation at the “Città della Salute e della Scienza” Hospital of Torino, starting from January 2018.ResultsAt least one micronutrient deficiency was present in 85.5% of pre-BS patients. Vitamin D deficiency was the most prevalent (74.5%), followed by folate (33.5%), iron (32%), calcium (13%), vitamin B12 (10%), and albumin (5.5%) deficiency. CRP values were high (>  5 mg/L) in 65% of the patients. These individuals showed increased rate of iron, folate, vitamin B12 deficiency, and a higher number of micronutrient deficiencies. In a multiple logistic regression model, increased CRP levels were significantly associated with deficiencies of vitamin B12 (OR =  5.84; 95% CI 1.25–27.2;p = 0.024), folate (OR = 4.02; 1.87–8.66;p 
Source: Journal of Endocrinological Investigation - Category: Endocrinology Source Type: research

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CONCLUSION: gluten-free diet, as followed by celiac patients, usually entails certain deficiencies such as group-B vitamins, vitamin D, calcium, iron, folic acid, and fiber, which is mainly due to the poor nutritional quality of gluten-free products as compared to their equivalents with gluten, and a scarce monitoring by health professionals. PMID: 32960627 [PubMed - as supplied by publisher]
Source: Nutricion Hospitalaria - Category: Nutrition Authors: Tags: Nutr Hosp Source Type: research
If you believe those upbeat, seductive advertisements, men only need to pop a pill to awaken their dormant sex life. Whether the problem is erectile dysfunction (ED) — the inability to maintain an erection for sex — or low libido, ED medications appear to be the quickest and easiest solution. While these drugs work for most men, they are not right for everyone. ED drugs are relatively safe, but can cause possible side effects such as headaches, indigestion, and back pain. Plus, some men may not want their sex life dependent on regular medication, or simply can’t take them because of high or low blood pres...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Dental Health Diet and Weight Loss Exercise and Fitness Men's Health Source Type: blogs
CONCLUSIONS: Vegetarian bariatric patients in East and South-East Asia are an under-recognized patient cohort at risk of micronutrient deficiencies. There is a knowledge gap among regional surgeons in long-term nutritional assessment and management. PMID: 32800753 [PubMed - as supplied by publisher]
Source: Asian Journal of Surgery - Category: Surgery Authors: Tags: Asian J Surg Source Type: research
This study was part of the multicenter randomized controlled trial (DUCATI), including 444 patients undergoing a RYGB or a VLRL-RYGB. Laboratory results, use of multivitamin supplements and reoperations were collected at baseline and one year postoperative. Primary outcome measure was nutrient deficiency after one year postoperative. Secondary outcome measure was the reoperation rate due to malabsorption. In total, 227 patients underwent RYGB and 196 patients underwent VLRL-RYGB. Most common deficiencies at one year postoperative were Ferritin(17.2-18.2%), Iron(23.4-35.6%), Potassium(7.4-15.2%), Vitamin B12(9.0-9.9%) and V...
Source: The British Journal of Nutrition - Category: Nutrition Authors: Tags: Br J Nutr Source Type: research
AbstractBackgroundPatients undergoing laparoscopic Roux-en-Y gastric bypass (LRYGB) are under risk of micronutrient deficiencies. We aimed to assess the preoperative and postoperative micronutrient deficiencies in a sample of patients with obesity who underwent LRYGB.MethodsWe evaluated 169 patients —satisfying the National Institute of Health criteria for bariatric surgery—who underwent a LRYGB from January 2014 to July 2017. Before surgery, we recorded a detailed medical history for every patient, and after surgery, we instructed them to return at 1, 6, 12, 24, 36, and 48 months after su rgery.ResultsPre...
Source: Obesity Surgery - Category: Surgery Source Type: research
Conclusion: CSVT is a common clinical entity among the causes of IIHT, and it should be taken into consideration in this patient group. However, there is a need for a common guideline for laboratory and imaging methods to understand the etiopathogenesis of childhood IIHT and determine the patients at risk.
Source: The Neurologist - Category: Neurology Tags: Original Article Source Type: research
Authors: Schiavo L, Pilone V, Rossetti G, Romano M, Pieretti G, Schneck AS, Iannelli A Abstract Micronutrient deficiencies (MD) shortly after sleeve gastrectomy (SG) are frequent and patients with obesity often show MD preoperatively. Our aim was to assess whether the correction of MD before SG could play a role in preventing early postoperative MD. Eighty patients (58 females, 22 males) who underwent SG were evaluated retrospectively. Patients were divided according to whether they had received preoperative MD correction (Group A, n = 42; 30 females, 12 males) or not (Group B, n = 38; 28 females, 10 males). Micron...
Source: International Journal for Vitamin and Nutrition Research - Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research
AbstractBackgroundBariatric surgery represents the most effective treatment for obesity and its related comorbidities. The present study aims to evaluate the efficacy and safety of sleeve gastrectomy plus jejunojejunal bypass (SG + JJB).MethodsThis retrospective study included 244 obese patients with BMI  ≥ 35 kg/m2 undergoing SG + JJB (n = 83), SG (n = 82), and Roux-en-Y gastric bypass (RYGB) (n = 79). Postoperative weight loss, metabolic outcomes, nutrition status, and patients’ complaints at 1-year follow-up were compared. Subgroup analyses (36 pairs ...
Source: Obesity Surgery - Category: Surgery Source Type: research
Objectives: 1- To analyze the pre-surgical and post-surgical prevalence of iron deficiency, vitamin-B12, vitamin-D and calcium.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Source Type: research
In this study, we assess the prevalence of nutritional deficiencies in patients with clinically severe obesity in Singapore and examine factors associated with the deficiencies.MethodsThis is a prospective, observational study of 577 consecutive patients scheduled to undergo MBS. Nutritional profile including renal panel, calcium, phosphate, intact parathyroid hormone (iPTH), 25-hydroxyvitamin D (25(OH)D), vitamin B12, folate, ferritin, iron studies, hemoglobin, albumin, and alkaline phosphatase were analyzed.ResultsMean age was 40.6  ± 10.3 years, 61.2% female, and mean BMI 42.4 ±&t...
Source: Obesity Surgery - Category: Surgery Source Type: research
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