Empagliflozin's HFrEF Benefit Steady With Sacubitril/Valsartan Empagliflozin's HFrEF Benefit Steady With Sacubitril/Valsartan

The SGLT2 inhibitor empagliflozin works just as well when added on top of a second major agent used to treat patients with heart failure and reduced ejection fraction.Medscape Medical News
Source: Medscape Cardiology Headlines - Category: Cardiology Tags: Cardiology News Source Type: news

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We describe the stepwise management of anticoagulation in a coagulopathic patient with persistent cardiogenic shock following a coronary artery bypass procedure who underwent Impella 5.5 placement. A direct thrombin inhibitor-based purge solution was utilized while evaluating for heparin-induced thrombocytopenia. The use of a novel bicarbonate-based purge solution (BBPS) was successfully used due to severe coagulopathy. There were no episodes of pump thrombosis or episodes of severe bleeding on the BBPS and systemic effects of alkalosis and hypernatremia were minimal.
Source: Journal of Cardiac Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: CASE REPORT Source Type: research
CONCLUSIONS: Return to work after heart transplantation is variable, with a tendency to be low, and is lower in patients near to retirement age. Protective factors were related to the social, physical and mental environment.PMID:34562415 | DOI:10.1016/j.amjms.2021.06.022
Source: The American Journal of the Medical Sciences - Category: General Medicine Authors: Source Type: research
J Cardiopulm Rehabil Prev. 2021 Sep 22. doi: 10.1097/HCR.0000000000000621. Online ahead of print.ABSTRACTPURPOSE: Vasodilator stress cardiac magnetic resonance (VS-CMR) has become crucial in the workup of patients with known or suspected chronic coronary syndrome (CCS). Whether traditional exercise ECG testing (ExECG) contributes prognostic information beyond VS-CMR is unclear.METHODS: We retrospectively included 288 patients with known or suspected CCS who had undergone ExECG and subsequent VS-CMR in our institution. Clinical, ExECG, and VS-CMR variables were recorded. We defined the serious adverse events (SAE) as a comb...
Source: Journal of Cardiopulmonary Rehabilitation and Prevention - Category: Rehabilitation Authors: Source Type: research
J Cardiopulm Rehabil Prev. 2021 Sep 22. doi: 10.1097/HCR.0000000000000644. Online ahead of print.ABSTRACTPerformance of endurance exercise is associated with a broad range of cognitive benefits, with notable improvements shown across a wide variety of populations including healthy populations as well as those with impaired cognition. By examining the effects of exercise in general populations, as well in populations where cognitive deficits are pronounced, and critical to self-care, we can learn more about using exercise to ameliorate cognitive issues and apply that knowledge to other patient populations, such as those eli...
Source: Journal of Cardiopulmonary Rehabilitation and Prevention - Category: Rehabilitation Authors: Source Type: research
Curr Opin Organ Transplant. 2021 Sep 24. doi: 10.1097/MOT.0000000000000923. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: Transplantation continues to be the only treatment option for end-stage organ failure when other interventions have failed. Although short-term outcomes have improved due to advances in perioperative care, long-term outcomes continue to be adversely affected by chronic rejection. Little is known about the role microbiota play in modulating alloimmune responses and potentially contributing to graft failure. Initial data have identified a correlation between specific changes of the recipient and/or don...
Source: Current Opinion in Organ Transplantation - Category: Transplant Surgery Authors: Source Type: research
Infective endocarditis (IE) is an uncommon disease with a high morbidity and mortality. The basic pathology involves adherence of microorganisms to areas of endothelial damage or associated implanted medical devices, such as prosthetic valves or pacemakers, resulting in localized infection and formation of vegetations. Complications include sepsis, secondary infections (e.g. spinal osteomyelitis), heart failure and embolization. Staphylococci, streptococci and enterococci are the predominant causes of IE.
Source: Medicine - Category: Internal Medicine Authors: Tags: Cardiovascular infections Source Type: research
Condition:   Heart Failure Intervention:   Sponsor:   Jean-Marc BOIVIN Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Heart Failure Interventions:   Behavioral: Sensor-controlled digital game (SCDG);   Behavioral: Sensor Only Sponsor:   University of Texas at Austin Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Heart Failure Intervention:   Sponsor:   Jean-Marc BOIVIN Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Heart Failure Interventions:   Behavioral: Sensor-controlled digital game (SCDG);   Behavioral: Sensor Only Sponsor:   University of Texas at Austin Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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