Articular angioedema in patients with chronic spontaneous urticaria is frequently misdiagnosed as arthritis

Publication date: October 2020Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 8, Issue 9Author(s): Elias Toubi, Ana Maria Giménez-Arnau, Marcus Maurer, Zahava Vadasz
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research

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Gail initiated an enlightening string on the Wheat Belly 10-Day Grain Detox Facebook page in which she shared something she lost on the program, then something she gained while following the Wheat Belly 10-Day Grain Detox and lifestyle. Here is how it unfolded in the first few hours: “I could easily post a ‘before’ and ‘now’ picture. However, I find that most of us have so many more NSV than scale victories. “So, on that note, to encourage newbies to keep on keeping on, let’s all post at least one thing that we’ve lost and one thing that we’ve gained on this journey to ...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Open Detox Inflammation joint pain wheat belly Source Type: blogs
Publication date: Available online 7 June 2020Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Toubi Elias, Ana Maria Giménez-Arnau, Maurer Marcus, Vadasz Zahava
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Authors: Han JH, Je YJ, Yoon HJ, Ahn JG, Lee JS, Park JW, Park HJ Abstract Cryopyrin-associated periodic syndrome (CAPS) is a hereditary autoinflammatory syndrome caused by mutations in NLRP3 (encoding cryopyrin), which presents with fever, fatigue and arthralgia. Thus far, however there have been no reports of CAPS in Korea. Herein, we report 3 cases of CAPS for the first time in Korea. The first case, a 28-year-old man with recurrent urticaria, arthralgia and fever induced by cold, all of which were observed in his father, showed elevated erythrocyte sedimentation rate and C-reactive protein. He exhibited a p.Gly...
Source: Allergy, Asthma and Immunology Research - Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research
Shanshan Zhang1, Dongli Yuan2 and Ge Tan1* 1Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China 2The Institute of Medical Information, Chongqing Medical University, Chongqing, China Primary systemic vasculitis can affect every structure in both the central and peripheral nervous system, causing varied neurological manifestations of neurological dysfunction. Early recognition of the underlying causes of the neurological symptoms can facilitate timely treatment and improve the prognosis. This review highlights the clinical manifestations of primary systemic vasc...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Rituximab is a chimeric monoclonal anti-CD20 antibody with wide use in cancer (lymphoma) and connective tissue diseases (rheumatoid arthritis, and vasculitis)1. Hypersensitivity reactions to rituximab can range from type I IgE-mediated reaction (urticaria, shortness of breath, hypotension, or anaphylaxis), to cytokine-mediated reaction (fevers, chills, rigors), or a mix of both, thus limiting the use of rituximab as first line therapy for many cases. Desensitization is a new therapeutic approach which can be performed with rituximab to offset these reactions.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Challenging Clinical Cases Source Type: research
Rituximab is a chimeric monoclonal anti-CD20 antibody with wide use in cancer (lymphoma) and connective tissue diseases (rheumatoid arthritis and vasculitis).1 Hypersensitivity reactions to rituximab can range from type I immunoglobulin E (IgE)-mediated reaction (urticaria, shortness of breath, hypotension, or anaphylaxis) to cytokine-mediated reaction (fevers, chills, rigors) or a mix of both, thus limiting the use of rituximab as first-line therapy for many cases. Desensitization is a new therapeutic approach that can be performed with rituximab to offset these reactions.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Challenging Clinical Cases Source Type: research
Patient Presentation A 9-year-old male came to clinic with a 1 month history of painful joint swelling. One month ago he started having right ankle pain that was intermittent but consistent. One day ago his right wrist, right ankle and bilateral knees had some swelling but no erythema or warmth. He says that he has pain in them when he moves but not when he is resting and he denies any joint stiffness or gelling. He also had 1-2 days of multiple red skin lesions on his extremities and trunk, not overlying the affected joints. The skin lesions do not come and go and do not itch. They are mainly discrete circular lesions wi...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
Treat-to-target therapy approaches are established for chronic diseases such as diabetes, hypertension, and more recently rheumatoid arthritis, resulting in improved patient outcomes. These approaches do not u...
Source: Allergy, Asthma and Clinical Immunology - Category: Allergy & Immunology Authors: Tags: Short Report Source Type: research
Authors: Binder V, Weeke E, Olsen JH, Anthonisen P, Rus P Abstract A group of 152 patients with a verified diagnosis of ulcerative colitis (including haemorrhagic proctitis) was compared with a control group with an identical sex ratio, age, and social class distribution. All patients attended an ulcerative colitis out-patient clinic, and had been examined and followed by the members of the team. By the use of questionnaires information was gathered concerning familial incidence of the following diseases: ulcerative colitis, regional ileitis, cancer of the colon and rectum, allergic diseases of the immediate type (...
Source: Scandinavian Journal of Gastroenterology - Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research
Conclusions: Neutrophilic epitheliotropism is a new sensitive and specific histopathological clue for NUD, a histopathological reaction pattern within the spectrum of neutrophilic dermatoses that needs to be differentiated from conventional urticaria.
Source: The American Journal of Dermatopathology - Category: Pathology Tags: Original Study Source Type: research
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