Is it Possible to Prevent Cerebral Embolization by Improving the Design and Technology of Carotid Stent Implantation?

Is it Possible to Prevent Cerebral Embolization by Improving the Design and Technology of Carotid Stent Implantation? Expert Rev Cardiovasc Ther. 2020 Oct 06;: Authors: Osipova O, Popova I, Starodubtsev V, Bugurov S, Karpenko A Abstract INTRODUCTION: The prevention of atherosclerotic plaque fragmentation during carotid artery stenting is a fundamental problem in decreasing the risk for disability of patients. The goal of this review is to clarify whether the stent design can have a decisive impact on the rate of intraoperative and postoperative complications. AREAS COVERED: Different designs of the carotid stents are briefed and the advantages and disadvantages of different stent designs are discussed as well as the results of their clinical use. Various solutions are presented to reduce cerebral embolism during carotid artery stenting. EXPERT OPINION: There is no conclusive evidence for the benefits of closed cell and hybrid stents. The stent design cannot completely resolve the problem of cerebral embolism. Most of the events of cerebral microembolism occur at the stages of stent delivery rather than protrusion of an atherosclerotic plaque in the long-term follow-up. Most likely, minimization of the risks for periprocedural and postprocedural strokes requires not only the new solutions in stent design as well as the corresponding delivery systems and brain embolic protection systems, but also the new strategies of preprocedural drug stabilizatio...
Source: Expert Review of Cardiovascular Therapy - Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research

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Aging (Albany NY). 2021 Sep 22;13(undefined). doi: 10.18632/aging.203557. Online ahead of print.ABSTRACTINTRODUCTION: Cerebral small vessel disease (SVD) is prevalent in the elderly population and is associated with increased risk of dementia, stroke and disability. Currently there are no clear targets or strategies for the treatment of cerebral SVD. We set out to identify modifiable vascular treatment targets.PATIENTS AND METHODS: 112 participants with and without a history of CVD underwent macrovascular, microvascular and endothelial function tests and an MRI head scan.RESULTS: Increased carotid intima media thickness an...
Source: Aging - Category: Biomedical Science Authors: Source Type: research
STROKE remains one of the leading causes and death and disability worldwide, yet little can be done to prevent an incident. Changing one's lifestyle habits can, however, curtail the likelihood of an incident. How often you nap could determine your risk of the life-threatening condition.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
CONCLUSIONS: In this study, BoNT-A and intensive rehabilitation showed improvement in spasticity and UL function. A high therapeutic effect is expected in patients with moderate impairment levels who have voluntary movement in whole UL or in UL except for the wrist.IMPLICATIONS FOR REHABILITATIONHierarchical cluster analysis focusing on the Fugl-Meyer Assessment of the Upper Extremity sub-categories may be useful for studies aimed to improve the upper arm function.Botulinum Neurotoxin A therapy (BoNT-A) and intensive rehabilitation in post-stroke patients showed improvement in spasticity and upper arm function.The degree o...
Source: Disability and Rehabilitation - Category: Rehabilitation Authors: Source Type: research
CONCLUSIONS: SSRIs are effective and well-tolerated to promote motor recovery after stroke, but may increase the risk of seizures and gastrointestinal adverse effects.PMID:34538154 | DOI:10.1080/14737175.2021.1982696
Source: Expert Review of Neurotherapeutics - Category: Neurology Authors: Source Type: research
CONCLUSION: The study showed that the SBAP was effective in minimizing the fear-related maladaptive behaviour in post-stroke survivors.PMID:34542039 | DOI:10.3233/NRE-210144
Source: NeuroRehabilitation - Category: Rehabilitation Authors: Source Type: research
CONCLUSIONS: ICF classification of persons post stroke during rehabilitation recovery was feasible. The Generic-6 FS detected changes in functioning and health in persons recovered for rehabilitation after stroke and distinguished between different recovery rates of persons in the acute and chronic phase after stroke.PMID:34542256 | DOI:10.23736/S1973-9087.21.06706-X
Source: European Journal of Physical and Rehabilitation Medicine - Category: Rehabilitation Authors: Source Type: research
CONCLUSIONS: SSRIs are effective and well-tolerated to promote motor recovery after stroke, but may increase the risk of seizures and gastrointestinal adverse effects.PMID:34538154 | DOI:10.1080/14737175.2021.1982696
Source: Expert Review of Neurotherapeutics - Category: Neurology Authors: Source Type: research
Disabil Rehabil. 2021 Sep 19:1-9. doi: 10.1080/09638288.2021.1973121. Online ahead of print.ABSTRACTPURPOSE: To compare home-based unimanual mirror therapy (UMT) and bimanual mirror therapy (BMT) for upper limb recovery in subacute/chronic stroke individuals with moderate-to-severe arm impairment.METHOD: Twenty-two participants were randomized into 1 of 3 groups: UMT, BMT or traditional occupational therapy (TOT) home-based programs. The intervention was 6-weeks and consisted of OT 2 days a week, weekly sessions with the research OT, and 30-minutes of the home-based program 5 days a week, according to group allocation. The...
Source: Disability and Rehabilitation - Category: Rehabilitation Authors: Source Type: research
CONCLUSIONS: SSRIs are effective and well-tolerated to promote motor recovery after stroke, but may increase the risk of seizures and gastrointestinal adverse effects.PMID:34538154 | DOI:10.1080/14737175.2021.1982696
Source: Expert Review of Neurotherapeutics - Category: Neurology Authors: Source Type: research
CONCLUSIONS: ICF classification of persons post stroke during rehabilitation recovery was feasible. The Generic-6 FS detected changes in functioning and health in persons recovered for rehabilitation after stroke and distinguished between different recovery rates of persons in the acute and chronic phase after stroke.PMID:34542256 | DOI:10.23736/S1973-9087.21.06706-X
Source: European Journal of Physical and Rehabilitation Medicine - Category: Rehabilitation Authors: Source Type: research
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