A rare case of malignant vagus nerve sheath tumor presenting with multiple cranial nerve dysfunction in a dog.

A rare case of malignant vagus nerve sheath tumor presenting with multiple cranial nerve dysfunction in a dog. Can Vet J. 2020 Oct;61(10):1049-1054 Authors: Giraud L, Lezmi S, Gomes E, Cauzinille L Abstract A 5-year-old intact male Gascon Saintongeois dog was presented with a 6-month history of coughing, laryngeal paralysis, a deglutition disorder of gradual onset, and left-sided Horner's syndrome. The dog was admitted as an emergency for acute central vestibular signs. Magnetic resonance images identified a left extra-axial brainstem lesion extending caudally from the medulla to the vagosympathetic trunk. Histological and immunohistological examination revealed a high grade epithelioid malignant peripheral nerve sheath tumor (MPNST). This case report is the first description of a MPNST of the vagus nerve compressing the brainstem and causing multiple cranial nerve dysfunction in a dog. Key clinical message: Nerve sheath tumors have been reported in many locations arising from spinal nerve roots and cranial nerves. Although the trigeminal nerve is the most commonly affected nerve, other cranial nerves such as the vagus can be affected. PMID: 33012818 [PubMed - in process]
Source: The Canadian Veterinary Journal - Category: Veterinary Research Authors: Tags: Can Vet J Source Type: research