Serum vitamin D level is related to disease progression in primary biliary cholangitis.

Serum vitamin D level is related to disease progression in primary biliary cholangitis. Scand J Gastroenterol. 2020 Oct 06;:1-8 Authors: Wang Z, Peng C, Wang P, Sui J, Wang Y, Sun G, Liu M Abstract BACKGROUND AND AIM: A nonskeletal role of vitamin D in primary biliary cholangitis (PBC) patients is not yet clear. The purpose of this study is to investigate the serum vitamin D level in patients with PBC and to explore whether serum vitamin D level is related to disease progression. METHODS: The serum levels of 25(OH)D3 were measured in 185 PBC patients and 141 healthy controls. The association with vitamin D levels and disease progression, particularly natural course, was assessed. RESULTS: Serum vitamin D levels were measured in 185 patients with PBC. The mean level of vitamin D in advanced stage patients was lower than that in early stage patients (9.15 ± 5.33 ng/ml vs. 13.68 ± 6.33 ng/ml, p = .000). In the follow-up patients, the vitamin D level in the taken calcitriol patients showed an upward trend, while the un-taken calcitriol patients was opposite. Besides, vitamin D levels were correlated with the changes of bilirubin, albumin (ALB) and APRI (p
Source: Scandinavian Journal of Gastroenterology - Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Related Links:

We report the case of a 10-year-old Chinese boy complaining of yellowish-brown teeth with extensive caries. Diagnoses: Clinical and laboratory examinations were performed, and VDDR-I was confirmed. Scanning electron microscopy confirmed amelogenesis imperfecta. Interventions: The patient had been taking drugs intervention for VDDR-I from the age of 3 years. The decayed teeth were treated, and metal-preformed crowns were placed to prevent further impairment. Sequence tooth extraction and remineralization therapy were also performed. Outcomes: After 3 years of follow-up, the patient exhibited normal tooth replacemen...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
AbstractIntroductionIn pregnancy, vitamin D deficiency is associated with increased risk of fetal growth restriction and preeclampsia. The underlying mechanisms are not known but placental dysfunction is believed to play a role in fetal growth restriction and preeclampsia. In a Danish population, where health authorities recommend a 10 µg/day vitamin D supplement during pregnancy, we explored current use of vitamin D supplements and vitamin D status. In term placentas, alterations in vitamin D metabolism and placental growth evaluated by the key placental growth factor PAPP‐A and their relation to vitamin D insuffi...
Source: Acta Obstetricia et Gynecologica Scandinavica - Category: OBGYN Authors: Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
In conclusion, sitting for prolonged periods of time without interruption is unfavorably associated with DBP and HDL cholesterol. Exercise Slows Inappropriate Growth of Blood Vessels in a Mouse Model of Macular Degeneration Excessive growth of blood vessels beneath the retina is a proximate cause of blindness in conditions such as macular degeneration. Researchers here provide evidence for physical activity to be influential in the pace at which this process of tissue...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
CONCLUSIONS: These findings suggest that physical activity and BMI had a significant effect on the metabolism of bone and vitamin D, but the effect of BMI was different in underweight, normal weight or obese subjects. In obesity the real vitamin D deficiency could be estimate by serum 1,25(OH)2D concentrations whose lower levels contribute to the higher PTH production and consequently to bone loss and to a greater fracture risk. PMID: 32515572 [PubMed - in process]
Source: Panminerva Medica - Category: General Medicine Tags: Panminerva Med Source Type: research
Conclusions: These findings will provide guidance to clinicians and patients on the use of vitamin D for PCOS with dyslipidemia. Ethics and dissemination: This study is a protocol for a systematic review of vitamin D as a treatment of dyslipidemia in PCOS patients. Systematic review registration: INPLASY202050007.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research
Authors: Mahmoudzadeh H, Nikibakhsh AA, Pashapour S, Ghasemnejad-Berenji M Abstract BACKGROUND: A link between vitamin D deficiency and susceptibility to bacterial and viral infections has recently been suggested. AIM: To investigate a possible association between vitamin D deficiency and urinary tract infection (UTI). METHODS: A case-control study was undertaken comprising 75 children aged 2-7 years with UTI (cases) compared with 75 healthy controls in terms of serum 25 hydroxyvitamin D [25(OH)D] levels. Serum 25(OH)D levels were measured using a chemiluminescence assay. For cases, dimercaptosuccinic ...
Source: Paediatrics and international child health - Category: Pediatrics Tags: Paediatr Int Child Health Source Type: research
Conclusions: In our study including female adolescents with idiopathic S shaped moderate scoliosis, plantar pressure and stabilometric parameters were influenced by the main scoliotic curve.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
CONCLUSIONS: Vitamin D has both a direct and an indirect role in the regulation of sleep. Although vitamin D deficiency has been associated to sleep disorders, there is still scant evidence to concretely support the role of vitamin D supplementation in the prevention or the treatment of sleep disturbances; indeed more intervention studies are needed to better clarify these aspects. PMID: 32156230 [PubMed - as supplied by publisher]
Source: Current Pharmaceutical Design - Category: Drugs & Pharmacology Authors: Tags: Curr Pharm Des Source Type: research
ConclusionsThis patient presented with amnesia which is a rare presentation of hypoparathyroidism.
Source: Journal of Diabetes and Metabolic Disorders - Category: Endocrinology Source Type: research
Conclusions: Despite the common nutrition recommendations, there are differences between the Nordic countries in the implementation of the recommendations and policies to achieve adequate vitamin D intake and status. There is a need for wider Nordic collaboration studies as well as strategies to improve vitamin D status, especially in risk groups. PMID: 31916497 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Public Health - Category: International Medicine & Public Health Authors: Tags: Scand J Public Health Source Type: research
More News: Bilirubin | Gastroenterology | PET Scan | Study | Vitamin D | Vitamin D Deficiency | Vitamins