Crocodile-like sensory scales in a Late Jurassic theropod dinosaur.

Crocodile-like sensory scales in a Late Jurassic theropod dinosaur. Curr Biol. 2020 Oct 05;30(19):R1068-R1070 Authors: Bell PR, Hendrickx C Abstract Early in amniote evolution, epidermal scales evolved in stem reptiles as an efficient barrier against water loss and ultraviolet radiation, making them a key development in the transition to a fully terrestrial existence [1]. Accordingly, epidermal scales are not simple inert structures but highly-evolved organs suited to perform a broad suite of functions. Here, we provide new data on the epidermal complexity of a non-avian theropod, Juravenator starki, from the Torleite Formation (upper Kimmeridgian), Bavaria, Germany [2]. Although epidermal scales have been noted previously on the tail of Juravenator, we report a unique scale type with distinctive circular nodes that we identify as integumentary sense organs, analogous to those in modern crocodylians. The surprising presence of such structures suggests the tail had a sensory function, which is nevertheless congruent with the inferred ecology of Juravenator and the evolution of integumentary sense organs among archosaurs. PMID: 33022234 [PubMed - as supplied by publisher]
Source: Current Biology - Category: Biology Authors: Tags: Curr Biol Source Type: research

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In this study, we present a new method for the simultaneous detection of CXCR4, mesodermal markers and NCCs markers during chicken embryo developmental stages HH18 –HH25 by combining double whole-mount in situ hybridization (ISH) and immunostaining on floating vibratome sections. The simultaneous detection of CXCR4 and markers for the mesodermal and neural crest cells in multiple labelling allowed us to compare complex gene expression patterns and it could b e easily used for a wide range of gene expression pattern analyses of other chicken embryonic tissues. All steps of the procedure, including the preparation of p...
Source: Histochemistry and Cell Biology - Category: Biomedical Science Source Type: research
Publication date: Available online 8 October 2020Source: Research in Veterinary ScienceAuthor(s): Ali Raza Jahejo, Wen-xia Tian
Source: Research in Veterinary Science - Category: Veterinary Research Source Type: research
This study increases the amount of genetic information on viruses present in laboratory rabbits.
Source: Archives of Virology - Category: Virology Source Type: research
long Xu Janus kinase (JAK) inhibitors have been developed as novel immunomodulatory drugs and primarily used for treating rheumatoid arthritis and other inflammatory diseases. Recent studies have suggested that this category of anti-inflammatory drugs could be potentially useful for the control of inflammation “storms” in respiratory virus infections. In addition to their role in regulating immune cell functions, JAK1 and JAK2 have been recently identified as crucial cellular factors involved in influenza A virus (IAV) replication and could be potentially targeted for antiviral therapy. Gingerenone ...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
Abstract In January 2020, the subclade of highly pathogenic avian influenza (H5N6) virus infected migratory whooper swans and mute swans in Xinjiang, western China. The virus is lethal to chickens and ducks but has low pathogenicity in mice. Antigenically, this subclade is similar to the H5N1 vaccine seed virus Re-11. PMID: 33030424 [PubMed - as supplied by publisher]
Source: Emerging Infectious Diseases - Category: Infectious Diseases Authors: Tags: Emerg Infect Dis Source Type: research
Abstract An outbreak of low-pathogenicity avian influenza A(H7N3) virus of North American wild bird lineage occurred on commercial turkey farms in North Carolina and South Carolina, USA, during March-April 2020. The virus mutated to the highly pathogenic form in 1 house on 1 farm via recombination with host 28S rRNA. PMID: 33030423 [PubMed - as supplied by publisher]
Source: Emerging Infectious Diseases - Category: Infectious Diseases Authors: Tags: Emerg Infect Dis Source Type: research
In vitro development of the complete life cycle of Eimeria species has been achieved in primary cultures of avian epithelial cells with low efficiency. The use of immortalized cell lines simplifies procedures but only allows partial development through one round of parasite invasion and intracellular replication. We have assessed the suitability of Madin-Darby Bovine Kidney (MDBK) cells to support qualitative and quantitative studies on sporozoite invasion and intracellular development of Eimeria tenella. Analysis of parasite ultrastructure by transmission electron microscopy and serial block face—scanning electron m...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
Authors: Brik A, Weber DG, Casjens S, Rozynek P, Meier S, Behrens T, Stamatis G, Darwiche K, Theegarten D, Brüning T, Johnen G Abstract Background: MYC (v-myc avian myelocytomatosis viral oncogene homolog) is one of the most frequently amplified genes in lung tumors. For the analysis of gene copy number variations, dPCR (digital PCR) is an appropriate tool. The aim of our study was the assessment of dPCR for the detection of MYC copy number variations (CNV) in lung tissue considering clinicopathological parameters. Material and Methods. MYC status was analyzed with dPCR as well as qPCR (quantitative PCR) using...
Source: Disease Markers - Category: Laboratory Medicine Tags: Dis Markers Source Type: research
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Source: Avian Pathology - Category: Pathology Authors: Tags: Avian Pathol Source Type: research
Abstract Almost two decades ago in addition to a compulsory M. gallisepticum (Mg) monitoring programme of breeding stock based on European Union regulations, the Dutch poultry industry added national regulations to further reduce the Mg prevalence in Dutch commercial poultry. Currently, all commercial chicken and turkey flocks except broilers are monitored for Mg. All breeding flocks on a farm where one or more flocks tested Mg positive are culled. Mg positive layer pullets are channelled and layer pullets placed on Mg positive multi-age farms are vaccinated. The monitoring data obtained were analysed covering a p...
Source: Avian Pathology - Category: Pathology Authors: Tags: Avian Pathol Source Type: research
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