Factors affecting weight loss variability in obesity

Current obesity treatment strategies include diet, exercise, bariatric surgery, and a limited but growing repertoire of medications. Individual weight loss in response to each of these strategies is highly variable. Here we review research into factors potentially contributing to inter-individual variability in response to treatments for obesity, with a focus on studies in humans. Well-recognized factors associated with weight loss capacity include diet adherence, physical activity, sex, age, and specific medications.
Source: Metabolism - Clinical and Experimental - Category: Biomedical Science Authors: Source Type: research

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Surg Obes Relat Dis. 2021 Aug 30:S1550-7289(21)00418-4. doi: 10.1016/j.soard.2021.08.019. Online ahead of print.NO ABSTRACTPMID:34538571 | DOI:10.1016/j.soard.2021.08.019
Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery - Category: Surgery Authors: Source Type: research
This article discusses surgical postoperative complications and metabolic complications.PMID:34537140 | DOI:10.1016/j.suc.2021.05.017
Source: The Surgical Clinics of North America - Category: Surgery Authors: Source Type: research
Conclusions: Besides leading to excess BMI loss of 61.2%, bariatric surgery also resulted in diabetes remission in 55.2% of the patients. Amongst various pre-operative scores, Advanced-DiaRem has the highest predictive accuracy for T2DM remission.
Source: Journal of Minimal Access Surgery - Category: Surgery Authors: Source Type: research
AbstractBackgroundBariatric surgery has been increasingly becoming popular due to the advancements in minimally invasive approaches and techniques. The aim of this study was to compare the long-term outcomes and clinical relevance of laparoscopic sleeve gastrectomy (LSG) and laparoscopic greater curvature plication (LGCP) in a matched controlled single-bariatric centre study.MethodsWe collected data from 163 patients who underwent either LSG or LGCP over a period of at least 5  years. The outcome parameters included body mass index (BMI) changes, causes of revision surgery, endoscopic findings and effects on obesity-r...
Source: Obesity Surgery - Category: Surgery Source Type: research
Conclusion: BMS may be considered as a safe treatment option for patients suffering from clinically severe obesity during the COVID-19 pandemic. Due care must be taken to protect patients and healthcare workers and all procedures must be conducted in line with the safe practice guidelines.
Source: Journal of Minimal Access Surgery - Category: Surgery Authors: Source Type: research
ConclusionsWe attach a video that illustrates the management and technique used to deal with the weight regain after primary bariatric surgery RYGB. We consider that in patients with super morbid obesity refractory to RYGB, conversion to SADIS is an excellent alternative due to its safety and feasibility.
Source: Obesity Surgery - Category: Surgery Source Type: research
Obesity and its associated comorbidities are rapidly increasing in the US population. Therefore, metabolic associated fatty liver disease (MAFLD), previously known as nonalcoholic fatty liver disease (NAFLD), has become a leading indication for liver transplantation. Lifestyle modifications as a sole therapy have been insufficient to reduce the burden of chronic liver disease secondary to MAFLD. Endoscopic bariatric interventions (EBI) appear to be safe and effective therapies for obesity and chronic liver disease secondary to MAFLD. Gastric EBI include endoscopic sleeve gastroplasty (ESG) and intragastric balloons (IGB). ...
Source: Clinics in Liver Disease - Category: Gastroenterology Authors: Source Type: research
Ann Ital Chir. 2021;92:397-405.ABSTRACTMorbid obesity (BMI>40 kg/m2) is a challenging health condition with an increasing incidence in the last decades. Conventional therapy which consists in diet and lifestyle interventions, along with pharmaceutical therapy, has a limited effect on morbidly obese patients. In this context, bariatric surgery is the most effective approach, leading to significant weight loss, along with other beneficial effects like type 2 diabetes resolution or improvement of cardiovascular status. The bariatric surgery outcomes can widely vary among individuals, with a significant percentage of patien...
Source: Annali Italiani di Chirurgia - Category: Surgery Authors: Source Type: research
Considerable evidence documents the effectiveness and efficacy of bariatric surgery (BaS) in reducing the prevalence and severity of obesity-related comorbidities. Diastolic heart failure (DHF) is a condition with considerable morbidity and mortality, yet recalcitrant to medical-therapy. Our objectives were to assess whether BaS is associated with a decrease in hospital admissions for DHF; and further assess its impact upon DHF hospital admissions among patients with hypertension (HTN) and coronary artery disease (CAD).
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Tags: ASMBS Guidelines/Statements Source Type: research
CONCLUSION: The prevalence of patient-reported CAP increased after SG. Patients reporting CAP had reduced quality-of-life scores.PMID:34518144 | DOI:10.1016/j.soard.2021.07.014
Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery - Category: Surgery Authors: Source Type: research
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