P2X3 Receptor in Primary Afferent Neurons Mediates the Relief of Visceral Hypersensitivity by Electroacupuncture in an Irritable Bowel Syndrome Rat Model.

Conclusion: EA can regulate the P2X3 receptor protein and mRNA expression levels in the colon and related DRG of IBS rats with visceral pain and then regulate the excitatory properties of DRG neurons. PMID: 33014041 [PubMed]
Source: Gastroenterology Research and Practice - Category: Gastroenterology Tags: Gastroenterol Res Pract Source Type: research

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Am J Chin Med. 2021 Feb 20:1-30. doi: 10.1142/S0192415X21500154. Online ahead of print.ABSTRACTIrritable bowel syndrome (IBS) is a chronic dysfunction of the gastrointestinal tract, commonly characterized by abdominal pain or abdominal discomfort. These symptoms can substantially reduce the quality of life and work productivity of the patients. The exact pathogenesis of IBS remains unclear, as it has become apparent that multiple pathways are activated in the condition, including inflammation, immunology, neurology and psychology. Recent evidence has shown that symptoms in IBS are related to the dysfunction of the nervous ...
Source: The American Journal of Chinese Medicine - Category: Complementary Medicine Authors: Source Type: research
Many women suffer through years of painful menstrual periods before they are able to get an answer about what’s causing them: a common and often undiagnosed condition called endometriosis. What is endometriosis? Endometriosis is a condition that occurs when tissue much like the tissue that lines a woman’s uterus — called the endometrium — starts to grow in other places inside the body. Most commonly, these growths are within the pelvis, such as on the ovaries, the fallopian tubes, the outer surface of the uterus, or the bladder. During the menstrual cycle each month, the tissue lining the uterus gro...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Pain Management Stress Surgery Women's Health Source Type: blogs
Conclusions: EA treatment can decrease the expression of hypothalamic CRF and CRF-R1, relieve anxiety and depression, meanwhile reduce the expression of CRF-R1 in the gastrointestinal mucosa, increase ZO-1 expression, and adjust tight junctions (TJs) to repair the intestinal mucosal barrier. The above roles suggest that EA may play a dual role in alleviating the gastrointestinal and psychological symptoms of IBS, suggesting a potentially dual therapeutic role for EA in regulating disorders of gut-brain interaction in IBS rats. PMID: 31737064 [PubMed]
Source: Gastroenterology Research and Practice - Category: Gastroenterology Tags: Gastroenterol Res Pract Source Type: research
Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder characterized by abdominal pain and change of bowel habit without organic disease. A global perspective given by the World Gastroenterology...
Source: Trials - Category: General Medicine Authors: Tags: Study protocol Source Type: research
For over 20 years, Linda Buonanno lived in fear that her irritable bowel syndrome (IBS) would suddenly interrupt her daily routine with frequent trips to the bathroom and unbearable cramping. Buonanno, now a 71-year-old medical assistant and hairdresser from Methuen, Mass., tried everything from drugs to dairy-free diets. Nothing worked. She remembers a particularly tough period over 10 years ago, when she was working on the factory floor of a medical-device company for up to 10 hours a day, six days a week. When an IBS episode would strike, her co-workers would cover for her as she huddled in a corner, keeled over in pain...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized medicine Research Source Type: news
Conclusion: The conclusion of our systematic review will provide evidence to judge whether EA is an effective intervention for patient with IBS. PROSPERO registration number: PROSPERO CRD42018081610.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research
Follow me on Twitter @drClaire More and more, I have families in my practice who are trying out treatments and therapies I didn’t prescribe. Most of the time, it’s absolutely fine. Other times, it’s not. “Complementary and alternative medicine” is a broad term that refers to treatments that are not generally part of traditional Western medicine. It includes things like herbal remedies, dietary supplements or alternative diets, acupuncture, acupressure, homeopathy, Chinese remedies, Reiki, or hypnosis. It also includes things like yoga or meditation — and chiropractic medicine. Many of th...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Children's Health Complementary and alternative medicine Parenting Source Type: blogs
Sarah Fishman exudes vivaciousness and warmth. When describing her favorite activities, mainly swimming and rugby, her energy is infectious. It is hard to imagine that someone as lively as Sarah has been suffering from chronic pain her whole life. Since she was little, Sarah has struggled with Irritable Bowel Syndrome (IBS), a common intestinal disorder that causes stomach pain and colon issues. However, it wasn’t until her junior year of college that she started experiencing symptoms that were no longer recognizable. “My local gastroenterologist kept giving me treatments that weren’t doing anything,&rdqu...
Source: Thrive, Children's Hospital Boston - Category: Pediatrics Authors: Tags: Our Patients’ Stories Alyssa Lebel dysautonomia headaches irritable bowel syndrome Source Type: news
Publication date: Available online 23 June 2016 Source:EXPLORE: The Journal of Science and Healing Author(s): Jessie Pettit, Richard Glickman-Simon
Source: EXPLORE: The Journal of Science and Healing - Category: Complementary Medicine Source Type: research
DynaMed is an evidence-based clinical reference, which is updated daily through systematic surveillance and critical appraisal of the research literature. DynaMed editors and reviewers select content of interest for integrative medicine, summarize the current evidence, and describe challenges in evidence analysis and application. Evidence quality is rated level 1 (likely reliable) evidence for studies with clinical outcomes and minimal risk of bias, level 2 (mid-level) evidence for studies with clinical outcomes and significant methodological or statistical limitations, and level 3 (lacking direct) evidence for reports tha...
Source: Explore - Category: Nursing Authors: Source Type: research
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