Establishment of microbeam radiation therapy at a small animal irradiator

Microbeam radiation therapy (MRT) is a preclinical concept in radiation oncology that spare s normal tissue more effectively than conventional radiation therapy at equal tumour control. The radiation field consists of peak regions with doses of several hundred Gray while doses between the peaks (valleys) are below the tissue tolerance level. Widths and distances of the beams are in the sub-millimeter range for MRT. A similar alternative concept with beam widths and distances in the millimeter range is presented by minibeam radiation therapy.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Tags: Physics Contribution Source Type: research