Applicability of radiomics in interstitial lung disease associated with systemic sclerosis: proof of concept

ConclusionThe correlation of radiomics with GAP stage, but not with the visually defined features of ILD-HRCT, implies that radiomics might capture features indicating severity of SSc-ILD on HRCT, which are not recognized by visual analysis.Key Points• Radiomics features can predict GAP stage with a sensitivity of 84% and a specificity of almost 100%.• Extent of fibrosis on HRCT and a combined model of different visual HRCT-ILD features perform worse in predicting GAP stage.• The correlation of radiomics with GAP stage, but not with the visually defined features of ILD-HRCT, implies that radiomics might capture features on HRCT, which are not recognized by visual analysis.
Source: European Radiology - Category: Radiology Source Type: research