Zi Shen Huo Luo Formula Prevents Aldosterone-Induced Cardiomyocyte Hypertrophy and Cardiac Fibroblast Proliferation by Regulating the Striatin-Mediated MR/EGFR/ERK Signaling Pathway.

In conclusion, ZSHLF inhibits the downstream EGFR/ERK signaling pathway by blocking the striatin-mediated membrane localization of MR, which may be an important molecular mechanism by which ZSHLF improves aldosterone-induced myocardial remodeling. PMID: 33014117 [PubMed]

https://www.ncbi.nlm.nih.gov/pubmed/33014117?dopt=Abstract

Source: Evidence-based Complementary and Alternative Medicine - October 7, 2020 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research