Dexmedetomidine inhibits apoptosis of astrocytes induced by oxygen-glucose deprivation via targeting JAK/STAT3 signal pathway.
CONCLUSION: DEX protects astrocytes against apoptosis via inhibiting JAK2/STAT3 signal pathway and downregulating JMJD3 expression in vitro.
PMID: 33017590 [PubMed - as supplied by publisher]
Source: Brain Research - Category: Neurology Authors: Feng P, Zhang A, Su M, Cai H, Wang X, Zhang Y Tags: Brain Res Source Type: research