CD8 T cells drive anorexia, dysbiosis, and blooms of a commensal with immunosuppressive potential after viral infection [Immunology and Inflammation]

Infections elicit immune adaptations to enable pathogen resistance and/or tolerance and are associated with compositional shifts of the intestinal microbiome. However, a comprehensive understanding of how infections with pathogens that exhibit distinct capability to spread and/or persist differentially change the microbiome, the underlying mechanisms, and the relative contribution of individual...

Source: Proceedings of the National Academy of Sciences - October 5, 2020 Category: Science Authors: Lara Labarta–Baȷo, Anna Gramalla–Schmitz, Romana R. Gerner, Katelynn R. Kazane, Gregory Humphrey, Tara Schwartz, Karenina Sanders, Austin Swafford, Rob Knight, Manuela Raffatellu, Elina I. Zuniga Tags: Biological Sciences Source Type: research